SLC27A2 Antibody

說明書

中文名稱：

SLC27A2兔多克隆抗體
貨號：

CSB-PA021534ESR2HU
規格：

￥440
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) SLC27A2 Polyclonal antibody
Uniprot No.：

O14975
基因名：

SLC27A2
別名：

ACSVL1 antibody; FACVL1 antibody; FATP 2 antibody; FATP-2 antibody; FATP2 antibody; Fatty acid coenzyme A ligase, very long chain 1 antibody; Fatty acid transport protein 2 antibody; Fatty-acid-coenzyme A ligase antibody; hFACVL1 antibody; HsT17226 antibody; Long chain fatty acid CoA ligase antibody; Long-chain-fatty-acid--CoA ligase antibody; S27A2_HUMAN antibody; Slc27a2 antibody; Solute carrier family 27 (fatty acid transporter), member 2 antibody; Solute carrier family 27 member 2 antibody; THCA CoA ligase antibody; THCA-CoA ligase antibody; Very long chain acyl CoA synthetase antibody; Very long chain fatty acid CoA ligase antibody; Very long chain fatty acid coenzyme A ligase 1 antibody; very long-chain 1 antibody; Very long-chain acyl-CoA synthetase antibody; Very long-chain-fatty-acid-CoA ligase antibody; VLACS antibody; VLCS antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Very long-chain acyl-CoA synthetase protein (30-200AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Acyl CoA synthetase that activates long-chain and very long-chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl-CoA. Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid. Does not activate C24 bile acids, cholate and chenodeoxycholate. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Exhibits long-chain fatty acids (LCFA) transport activity and plays an important role in hepatic fatty acid uptake.; Exhibits both long-chain fatty acids (LCFA) transport activity and acyl CoA synthetase towards very long-chain fatty acids. Shows a preference for generating CoA derivatives of n-3 fatty acids, which are preferentially trafficked into phosphatidylinositol.; Exhibits long-chain fatty acids (LCFA) transport activity but lacks acyl CoA synthetase towards very long-chain fatty acids.
基因功能參考文獻：
1. In overweight/obese pregnancies, the increased FATP2 placental expression could contribute to increased fatty acid delivery to the fetus. PMID: 27016784
2. In mice Grassofermata decreased absorption of (13)C-oleate demonstrating its potential as a therapeutic agent. PMID: 26284975
3. Protective effects of breastfeeding are reflected in higher expression levels of SLC27A2, FASN, PPARalpha and INSR in blood cells. PMID: 24277691
4. these data support the conclusion that FATP2 has a dual function in the pathways linking the transport and activation of exogenous fatty acids. PMID: 24113382
5. FATP2a functions in fatty acid transport and activation and provides specificity toward n-3 fatty acids in which the corresponding n-3 acyl-CoAs are preferentially trafficked into acyl-CoA pools destined for phosphatidylinositol incorporation PMID: 21768100
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亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein. Peroxisome membrane; Peripheral membrane protein. Cell membrane; Multi-pass membrane protein. Microsome.
蛋白家族：

ATP-dependent AMP-binding enzyme family
組織特異性：

Expressed in liver, kidney, placenta and pancreas.
數據庫鏈接：

HGNC: 10996

OMIM: 603247

KEGG: hsa:11001

STRING: 9606.ENSP00000267842

UniGene: Hs.11729

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