RTCA Antibody

說明書

產品詳情

Uniprot No.：

O00442
基因名：

RTCA
別名：

RTCA antibody; RPC antibody; RPC1 antibody; RTC1 antibody; RTCD1 antibody; RNA 3'-terminal phosphate cyclase antibody; RNA cyclase antibody; RNA-3'-phosphate cyclase antibody; EC 6.5.1.4 antibody; RNA terminal phosphate cyclase domain-containing protein 1 antibody; RTC domain-containing protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the C-terminal region of Human RTCD1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
基因功能參考文獻：
1. Rtc1 forms a stable binary complex with a 3'-phosphate terminated RNA, but not with an identical 3'-OH terminated RNA PMID: 19690099
亞細胞定位：

Nucleus, nucleoplasm.
蛋白家族：

RNA 3'-terminal cyclase family, Type 1 subfamily
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 17981

OMIM: 611286

KEGG: hsa:8634

STRING: 9606.ENSP00000260563

UniGene: Hs.484222

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