RAB18 Antibody
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中文名稱：RAB18兔多克隆抗體
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貨號：CSB-PA878835ESR2HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA878835ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA878835ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) RAB18 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：AA959686 antibody; RAB18 antibody; RAB18 small GTPase antibody; RAB18; member RAS oncogene family antibody; RAB18_HUMAN antibody; RAB18LI1 antibody; Ras related protein Rab 18 antibody; Ras-asssociated protein RAB18 antibody; Ras-related protein Rab-18 antibody; RP11-148B2.1 antibody; WARBM3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Ras-related protein Rab-18 protein (1-206AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts. Plays a role in apical endocytosis/recycling. Plays a key role in eye and brain development and neurodegeneration.
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基因功能參考文獻：
- The authors found that the previously documented interaction between TRAPPII and COPI was also required for the recruitment of Rab18 to the lipid droplet. PMID: 28003315
- findings suggest that RAB18 rs3765133 polymorphism affects the development of specific brain regions, particularly the cerebellum, in healthy people. PMID: 24996981
- RAB18 is the direct target of miR-455-5p in gastric cancer. PMID: 27451075
- Warburg Micro syndrome is caused by RAB18 deficiency. PMID: 26063829
- These results suggest that Rab18 has an important role in viral assembly through the trafficking of the hepatitis C virus core protein to lipid droplets. PMID: 24997429
- High RAB18 expression is associated with glioma. PMID: 24477653
- Rab18-mediated membrane trafficking of FASN and NS3 facilitates dengue virus replication. PMID: 24696471
- Rab18 interacts with the HCV nonstructural protein NS5A. PMID: 23935497
- Hepatitis B virus X protein enhances proliferation of hepatoma cells through Rab18. PMID: 23471881
- Micro syndrome has been associated with causative mutations in three disease genes: RAB3GAP1, RAB3GAP2 and RAB18. Martsolf syndrome has been associated with a mutation in RAB3GAP2. [Review] PMID: 23176487
- performed autozygosity mapping in five consanguineous families with Warburg micro syndrome without RAB3GAP1/2 mutations and identified loss-of-function mutations in RAB18 PMID: 21473985
- Rab18 regulates lipid droplet-associated membrane formation PMID: 15914536
- analysis of a novel splice variant of human Rab18 gene PMID: 16147880
- Rab18 is reduced in pituitary tumors causing acromegaly and its overexpression reverts growth hormone hypersecretion. PMID: 18349058
- Rab18 and Rab43 have key roles in ER-Golgi trafficking. PMID: 18664496
- Rab18 is recruited to lipid droplets during lipolysis PMID: 16207721
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相關疾病：Warburg micro syndrome 3 (WARBM3)
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亞細胞定位：Apical cell membrane. Lipid droplet.
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蛋白家族：Small GTPase superfamily, Rab family
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組織特異性：Ubiquitous.
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數據庫鏈接：
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