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中文名稱：PTPRM兔多克隆抗體
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貨號：CSB-PA019058GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：tibody; hR PTPu antibody; Protein tyrosine phosphatase mu antibody; Protein tyrosine phosphatase mu precursor antibody; Protein tyrosine phosphatase receptor type M antibody; Protein tyrosine phosphatase receptor type mu polypeptide antibody; Protein-tyrosine phosphatase mu antibody; PTPRL1 antibody; Ptprm antibody; PTPRM protein antibody; PTPRM_HUMAN antibody; R PTP mu antibody; R-PTP-mu antibody; Receptor type tyrosine protein phosphatase mu antibody; Receptor-type tyrosine-protein phosphatase mu antibody; RPTP mu antibody; RPTPM antibody; RPTPU antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human PTPRM
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.
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基因功能參考文獻：
- Study determined that, in addition to the furin-processed form of PTPmicro, a pool of 200 kDa full-length PTPmicro exists at the plasma membrane that is cleaved directly by ADAM to generate a larger shed form of the PTPmicro extracellular segment. PMID: 24771611
- Decreased expression of PTPRM in breast cancer is correlated with poor prognosis and inversely correlated with disease-free survival. PMID: 23185569
- Loss of PTPmu by proteolysis causes glioblastoma. PMID: 22505657
- Results suggest that miR-221 and -222 regulate glioma tumorigenesis at least in part through the control of PTPmu protein expression. PMID: 21743492
- In A549 cells, diverse injurious stimuli dramatically reduced PTPmu protein expression. PMID: 21649524
- Loss of protein tyrosine phosphatase receptor type mu is associated with glioma cell migration and progression. PMID: 19304959
- RPTPmu may play a role in the regulation of cardiovascular functions PMID: 12895029
- PTPmu may regulate Rho-GTPase-dependent functions of IQGAP1 PMID: 16380380
- a 3.1 angstrom crystal structure of the RPTPmu ectodomain that forms a homophilic trans (antiparallel) dimer with an extended and rigid architecture, matching the dimensions of adherens junctions is described PMID: 17761881
- BCCIP is phosphorylated by the Src tyrosine kinase and dephosphorylated by the PTPmu tyrosine phosphatase; neurite outgrowth assays suggest that BCCIP and PTPmu are in a common signal transduction pathway. PMID: 18773424
- loss of cell surface PTPmu by proteolysis generates catalytically active PTPmu fragments that contribute to migration and survival of glioblastoma cells PMID: 19690139
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亞細胞定位：Membrane; Single-pass type I membrane protein.
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蛋白家族：Protein-tyrosine phosphatase family, Receptor class 2B subfamily
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數據庫鏈接：
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