PRPF18 Antibody

中文名稱：

PRPF18兔多克隆抗體
貨號(hào)：

CSB-PA003856
規(guī)格：

￥1090
圖片：
Western Blot analysis of HuvEc cells using PRPF18 Polyclonal Antibody

Western Blot analysis of K562 NIH-3T3 cells using PRPF18 Polyclonal Antibody
其他：

產(chǎn)品詳情

Uniprot No.：

Q99633
基因名：

PRPF18
別名：

PRPF18 antibody; HPRP18Pre-mRNA-splicing factor 18 antibody; PRP18 homolog antibody; hPRP18 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human PRPF18.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:5000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Participates in the second step of pre-mRNA splicing.
基因功能參考文獻(xiàn)：
1. These results validated the association of two previously known skin pigmentation genes, SLC24A5 (minimum p = 2.62 x 10(-14), rs1426654) and SLC45A2 (minimum p = 9.71 x 10(-10), rs16891982), and revealed the intergenic region of BEND7 and PRPF18 as a novel locus associated with this trait (minimum p = 4.58 x 10(-9), rs6602666). PMID: 28300201
2. We identified the pre-mRNA processing factor Prp18 as a stimulatory factor for influenza virus RNA synthesis. Prp18 facilitates the elongation reaction of viral polymerases by preventing the deleterious annealing of newly synthesized RNA to the template. Prp18 functions as a chaperone for NP to stimulate the formation of NP-RNA complexes. PMID: 27852861
3. Presented is solution structure of the splicing factor motif of hPrp18, which forms a compact fold with two a helices interacting head-to-tail and a fixed linker loop. PMID: 22213562
亞細(xì)胞定位：

Nucleus speckle.
蛋白家族：

PRP18 family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17351

OMIM: 604993

KEGG: hsa:8559

STRING: 9606.ENSP00000367835

UniGene: Hs.660649

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