PPP2R3B Antibody

說明書

產品詳情

Uniprot No.：

Q9Y5P8
基因名：

PPP2R3B
別名：

NY REN 8 antibody; NY REN 8 antigen antibody; P2R3B_HUMAN antibody; PP2A B'' subunit PR48 antibody; PP2A subunit B isoform PR48 antibody; PP2A subunit B PR48 isoform antibody; PPP2R3B antibody; PPP2R3L antibody; PPP2R3LY antibody; PR 48 antibody; PR48 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' beta antibody; Protein phosphatase 2 regulatory subunit B'' beta antibody; Protein phosphatase 2A 48 kDa regulatory subunit antibody; Serine/threonine protein phosphatase 2A 48kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human PR48.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
基因功能參考文獻：
1. PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6-chromatin licensing and CDT1 interaction PMID: 27974665
2. Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2+ binding EF-hands Scattering data. PMID: 25007185
亞細胞定位：

Nucleus.
數據庫鏈接：

HGNC: 13417

OMIM: 300339

KEGG: hsa:28227

STRING: 9606.ENSP00000375080

UniGene: Hs.124942

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