POP1 Antibody
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中文名稱：POP1兔多克隆抗體
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貨號：CSB-PA018372GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：POP1
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別名：4932434G09Rik antibody; hPOP1 antibody; KIAA0061 antibody; MGC17365 antibody; MGC36536 antibody; POP1 antibody; POP1_HUMAN antibody; Processing of precursor 1 antibody; Processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) antibody; Processing of precursors 1 antibody; Ribonucleases P/MRP protein subunit homolog antibody; Ribonucleases P/MRP protein subunit POP1 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human POP1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
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基因功能參考文獻：
- Biallelic POP1 mutations were identified in both. A missense mutation and a novel single base deletion were detected in proband 1, p.[Pro582Ser]:[Glu870fs*5]. Markedly reduced abundance of RMRP and elevated levels of pre5.8s rRNA was observed. In proband 2, a homozygous novel POP1 mutation was identified PMID: 28067412
- we reported the third case with POP1-related AAD. This phenotype may appropriately be termed AAD type 2. PMID: 27380734
- by inhibiting inflammasome assembly, provides a regulatory feedback loop that shuts down excessive inflammatory responses; Cryopyrin-Associated Periodic Syndrome patients exhibit reduced expression PMID: 26275995
- S-palmitoylation alters conformation or secondary structure of Trx1, as well as decreases the ability of Trx1 to transfer electrons from thioredoxin reductase to S-nitrosylated protein-tyrosine phosphatase 1B and S-nitroso-glutathione PMID: 25839653
- Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-trna 5' processing. PMID: 22991464
- POP1 gene expression is increased in classic variant of papillary thyroid carcinoma. PMID: 21509594
- A transient association of protein subunits may be inversely correlated to its involvement in pre-rRNA processing. PMID: 16723659
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相關疾病：Anauxetic dysplasia 2 (ANXD2)
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亞細胞定位：Nucleus, nucleolus.
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數據庫鏈接：
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