PID1 Antibody

中文名稱：

PID1兔多克隆抗體
貨號：

CSB-PA800096LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA800096LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA800096LA01HU at dilution of 1:100

Immunofluorescent analysis of PC-3 cells using CSB-PA800096LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PID1 Polyclonal antibody
Uniprot No.：

Q7Z2X4
基因名：

PID1
別名：

5033414K04Rik antibody; Ab1 119 antibody; FLJ20701 antibody; HMFN2073 antibody; MGC90850 antibody; NYGGF4 antibody; OTTHUMP00000164248 antibody; OTTHUMP00000204185 antibody; P CLI1 antibody; P-CLI1 antibody; PCLI1 antibody; PCLI1_HUMAN antibody; Phosphotyrosine interaction domain containing 1 antibody; Phosphotyrosine interaction domain-containing protein 1 antibody; PID1 antibody; Protein NYGGF4 antibody; PTB containing; cubilin and LRP1 interacting protein antibody; PTB-containing; cubilin and LRP1-interacting protein antibody; RGD1560766 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human PTB-containing, cubilin and LRP1-interacting protein (15-168AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PID1 Antibody (CSB-PA800096LA01HU)，的標記方式是Non-conjugated。對于PID1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA800096LB01HU	PID1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA800096LC01HU	PID1 Antibody, FITC conjugated
Biotin	CSB-PA800096LD01HU	PID1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Increases proliferation of preadipocytes without affecting adipocytic differentiation.
基因功能參考文獻：
1. Overall survival and radiation-free progression-free survival were longer in medulloblastoma patients whose tumors had higher PID1 mRNA levels. PMID: 24300787
2. overexpression of TFAM can restore mitochondrial function to normal levels in NYGGF4-overexpressing adipocytes PMID: 23274913
3. NYGGF4 plays a role in IR and its effects on IR could be reversed by metformin through activating IRS-1/PI3K/Akt and AMPK-PGC1-alpha pathways. PMID: 22968630
4. NYGGF4 acts directly on the IRS1/PI3K/AKT insulin pathway to reduce glucose uptake and transport, impairs mitochondrial function and causes insulin resistance, and thus may be a useful therapeutic target for obesity-associated insulin resistance. PMID: 22284633
5. Overexpression of NYGGF4 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of NYGGF4-induced insulin resistance. PMID: 20165904
6. TNFA up-regulated the expression of NYGGF4 during preadipocyte differentiation. PMID: 20140872
7. NYGGF4 over-expression impairs the insulin sensitivity of 3T3-L1 adipocytes through decreasing GLUT4 translocation and had no effects on the secretory function of adipocytes. PMID: 19849947
8. A novel gene named NYGGF4, which was expressed at a higher level in obese subjects, was isolated and characterized and could play a role in cell growth and adipogenesis process PMID: 16815647
9. Data show that NYGGF4 regulates the functions of IRS-1 and Akt, decreases GLUT4 translocation and reduces glucose uptake in response to insulin. PMID: 19079291
10. Q7Z2X4 protein (PID1) identified as a cytosolic ligand of LRP1 in a trimeric complex with Cubilin. Q7Z2X4 named PCLI1 (PTB-containing, Cubilin and LRP1 Interacting protein 1) PMID: 17124247
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亞細胞定位：

Cytoplasm.
組織特異性：

Expressed in subcutaneous fat, heart, skeletal muscle, brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte.
數據庫鏈接：

HGNC: 26084

OMIM: 612930

KEGG: hsa:55022

STRING: 9606.ENSP00000375907

UniGene: Hs.745038

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