PID1 Antibody, Biotin conjugated
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中文名稱：PID1兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA800096LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PID1 Polyclonal antibody
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Uniprot No.：
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基因名：PID1
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別名：5033414K04Rik antibody; Ab1 119 antibody; FLJ20701 antibody; HMFN2073 antibody; MGC90850 antibody; NYGGF4 antibody; OTTHUMP00000164248 antibody; OTTHUMP00000204185 antibody; P CLI1 antibody; P-CLI1 antibody; PCLI1 antibody; PCLI1_HUMAN antibody; Phosphotyrosine interaction domain containing 1 antibody; Phosphotyrosine interaction domain-containing protein 1 antibody; PID1 antibody; Protein NYGGF4 antibody; PTB containing; cubilin and LRP1 interacting protein antibody; PTB-containing; cubilin and LRP1-interacting protein antibody; RGD1560766 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human PTB-containing, cubilin and LRP1-interacting protein (15-168AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Increases proliferation of preadipocytes without affecting adipocytic differentiation.
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基因功能參考文獻：
- Overall survival and radiation-free progression-free survival were longer in medulloblastoma patients whose tumors had higher PID1 mRNA levels. PMID: 24300787
- overexpression of TFAM can restore mitochondrial function to normal levels in NYGGF4-overexpressing adipocytes PMID: 23274913
- NYGGF4 plays a role in IR and its effects on IR could be reversed by metformin through activating IRS-1/PI3K/Akt and AMPK-PGC1-alpha pathways. PMID: 22968630
- NYGGF4 acts directly on the IRS1/PI3K/AKT insulin pathway to reduce glucose uptake and transport, impairs mitochondrial function and causes insulin resistance, and thus may be a useful therapeutic target for obesity-associated insulin resistance. PMID: 22284633
- Overexpression of NYGGF4 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of NYGGF4-induced insulin resistance. PMID: 20165904
- TNFA up-regulated the expression of NYGGF4 during preadipocyte differentiation. PMID: 20140872
- NYGGF4 over-expression impairs the insulin sensitivity of 3T3-L1 adipocytes through decreasing GLUT4 translocation and had no effects on the secretory function of adipocytes. PMID: 19849947
- A novel gene named NYGGF4, which was expressed at a higher level in obese subjects, was isolated and characterized and could play a role in cell growth and adipogenesis process PMID: 16815647
- Data show that NYGGF4 regulates the functions of IRS-1 and Akt, decreases GLUT4 translocation and reduces glucose uptake in response to insulin. PMID: 19079291
- Q7Z2X4 protein (PID1) identified as a cytosolic ligand of LRP1 in a trimeric complex with Cubilin. Q7Z2X4 named PCLI1 (PTB-containing, Cubilin and LRP1 Interacting protein 1) PMID: 17124247
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亞細胞定位：Cytoplasm.
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組織特異性：Expressed in subcutaneous fat, heart, skeletal muscle, brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte.
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數據庫鏈接：
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