PFDN5 Antibody

說明書

產品詳情

Uniprot No.：

Q99471
基因名：

PFDN5
別名：

1190001O17Rik antibody; 1700010A06Rik antibody; c myc binding protein antibody; c-myc binding protein MM 1 antibody; C-myc-binding protein Mm-1 antibody; D15Ertd697e antibody; EIG 1 antibody; Eig1 antibody; MGC5329 antibody; MGC71907 antibody; MM 1 antibody; MM1 antibody; Myc modulator 1 antibody; PFD5 antibody; PFD5_HUMAN antibody; PFDN5 antibody; Prefoldin 5 antibody; Prefoldin subunit 5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human PFDN5
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
基因功能參考文獻：
1. Results from a study on gene expression variability markers in early-stage human embryos shows that PFDN5 is a putative expression variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
2. interaction with p73 PMID: 11844794
3. MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc PMID: 16173081
4. Wnt4 gene, a member of the Wnt-beta-catenin pathway, was identified as a target gene of MM-1. PMID: 18281035
亞細胞定位：

[Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Nucleus.
蛋白家族：

Prefoldin subunit alpha family
組織特異性：

Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
數據庫鏈接：

HGNC: 8869

OMIM: 604899

KEGG: hsa:5204

STRING: 9606.ENSP00000334188

UniGene: Hs.655327

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