PDE6H Antibody

中文名稱：

PDE6H兔多克隆抗體
貨號：

CSB-PA617840LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA617840LA01HU diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) PDE6H Polyclonal antibody
Uniprot No.：

Q13956
基因名：

PDE6H
別名：

5''-cyclic phosphodiesterase subunit gamma antibody; CNCG_HUMAN antibody; GMP-PDE gamma antibody; Pde6h antibody; Retinal cone rhodopsin-sensitive cGMP 3'' antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma protein (1-83AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，PDE6H Antibody (CSB-PA617840LA01HU)，的標記方式是Non-conjugated。對于PDE6H Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA617840LB01HU	PDE6H Antibody, HRP conjugated	ELISA
FITC	CSB-PA617840LC01HU	PDE6H Antibody, FITC conjugated
Biotin	CSB-PA617840LD01HU	PDE6H Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
基因功能參考文獻：
1. These findings add PDE6H to the set of genes involved in autosomal-recessive cone disorders and demonstrate the importance of the inhibitory gamma subunit in cone phototransduction PMID: 22901948
2. Our results indicate that mutations in the PDE6H gene are not common, because only 1 of 240 patients with cone dystrophy showed a single nucleotide substitution in the 5' UTR of PDE6H mRNA PMID: 15629837
相關疾病：

Cone dystrophy, retinal 3A (RCD3A)
蛋白家族：

Rod/cone cGMP-PDE gamma subunit family
數據庫鏈接：

HGNC: 8790

OMIM: 601190

KEGG: hsa:5149

STRING: 9606.ENSP00000266395

UniGene: Hs.54471

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