PDE6H Antibody, HRP conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) PDE6H Polyclonal antibody
Uniprot No.：

Q13956
基因名：

PDE6H
別名：

5''-cyclic phosphodiesterase subunit gamma antibody; CNCG_HUMAN antibody; GMP-PDE gamma antibody; Pde6h antibody; Retinal cone rhodopsin-sensitive cGMP 3'' antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma protein (1-83AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
基因功能參考文獻(xiàn)：
1. These findings add PDE6H to the set of genes involved in autosomal-recessive cone disorders and demonstrate the importance of the inhibitory gamma subunit in cone phototransduction PMID: 22901948
2. Our results indicate that mutations in the PDE6H gene are not common, because only 1 of 240 patients with cone dystrophy showed a single nucleotide substitution in the 5' UTR of PDE6H mRNA PMID: 15629837
相關(guān)疾病：

Cone dystrophy, retinal 3A (RCD3A)
蛋白家族：

Rod/cone cGMP-PDE gamma subunit family
數(shù)據(jù)庫鏈接：

HGNC: 8790

OMIM: 601190

KEGG: hsa:5149

STRING: 9606.ENSP00000266395

UniGene: Hs.54471

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