PBXIP1 Antibody
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中文名稱：PBXIP1兔多克隆抗體
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貨號：CSB-PA017509GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：PBXIP1
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別名：PBXIP1 antibody; HPIPPre-B-cell leukemia transcription factor-interacting protein 1 antibody; Hematopoietic PBX-interacting protein antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Human PBXIP1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
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基因功能參考文獻：
- HPIP promotes gastric cancer cell proliferation through positive regulation of cap-dependent translation. PMID: 27748944
- Knockdown of HPIP suppressed TGF-beta1-induced EMT. PMID: 27178820
- our findings identified HPIP plays an important role in the progression and EMT of spinal glioblastoma, by which cell growth is improved. Thus, HPIP gene or protein could act as a useful target in the clinical practice. PMID: 26590606
- Copy number variations in PBXIP1 gene is associated with lung adenocarcinoma. PMID: 26497366
- HPIP may play critical role in oral carcinogenesis and is potential target for anticancer therapy, with particular emphasis on its involvement in differentiation and migration/metastasis. PMID: 25060351
- PBXIP1 is a novel protein overexpressed in astrocytoma and ependymoma, involved in tumor cell proliferation and migration PMID: 24470547
- These data highlight the important role of HPIP in liver cancer cell growth and suggest that HPIP may be a good target for liver cancer therapy. PMID: 24038948
- HPIP is a target of GATA1 and CTCF in erythroid cells and plays an important role in erythroid differentiation by modulating the PI3K/AKT pathway PMID: 22187427
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亞細胞定位：Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol (PubMed:12360403). Mainly localized in the cytoplasm, associated with microtubules (PubMed:10825160, PubMed:12360403). Detected in small amounts in the nucleus (PubMed:10825160).
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組織特異性：Expressed in early hematopoietic precursors.
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數據庫鏈接：
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