PACSIN3 Antibody
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中文名稱：PACSIN3兔多克隆抗體
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貨號：CSB-PA892456LA01HU
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規格：￥440
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圖片：
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Western Blot
Positive WB detected in: Rat liver tissue
All lanes: PACSIN3 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 49 kDa
Observed band size: 49 kDa -
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA892456LA01HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA892456LA01HU at dilution of 1:100 -
Immunofluorescence staining of HepG2 cells with CSB-PA892456LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). -
Western Blot
Positive WB detected in: MCF-7 whole cell lysate, PC-3 whole cell lysate, Mouse liver tissue
All lanes: PACSIN3 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 49 kDa
Observed band size: 49 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) PACSIN3 Polyclonal antibody
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Uniprot No.：
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基因名：PACSIN3
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別名：Endophilin 1 antibody; Endophilin I antibody; FLJ17861 antibody; OTTHUMP00000234262 antibody; OTTHUMP00000234263 antibody; OTTHUMP00000234264 antibody; PACN3_HUMAN antibody; Pacsin3 antibody; Protein kinase C and casein kinase substrate in neurons 3 antibody; Protein kinase C and casein kinase substrate in neurons protein 3 antibody; SDPIII antibody; SH3 domain containing protein 6511 antibody; SH3 domain-containing protein 6511 antibody; syndapin III antibody
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宿主：Rabbit
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human Protein kinase C and casein kinase substrate in neurons protein 3 protein (1-300AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，PACSIN3 Antibody (CSB-PA892456LA01HU)，的標記方式是Non-conjugated。對于PACSIN3 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC, IF
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:5000 IHC 1:20-1:200 IF 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
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基因功能參考文獻：
- Show that in neuroendocrine chromaffin cells fusion pore expansion and catecholamine release are limited specifically by mutation of syndapin 3. PMID: 24500282
- Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules PMID: 22573331
- PACSIN3 has a novel function as an up-regulator in the signaling of proHB-EGF shedding induced by TPA and angiotensin II PMID: 12952982
- PACSIN 3 acts as an auxiliary protein of TRPV4 channel that not only affects the channel's subcellular localization but also modulates its function in a stimulus-specific manner. PMID: 18174177
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亞細胞定位：Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
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蛋白家族：PACSIN family
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組織特異性：Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney.
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數據庫鏈接：
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