PACSIN3 Antibody, FITC conjugated
產(chǎn)品詳情
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產(chǎn)品名稱：
Rabbit anti-Homo sapiens (Human) PACSIN3 Polyclonal antibody
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Uniprot No.：
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基因名：
PACSIN3
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別名：
Endophilin 1 antibody; Endophilin I antibody; FLJ17861 antibody; OTTHUMP00000234262 antibody; OTTHUMP00000234263 antibody; OTTHUMP00000234264 antibody; PACN3_HUMAN antibody; Pacsin3 antibody; Protein kinase C and casein kinase substrate in neurons 3 antibody; Protein kinase C and casein kinase substrate in neurons protein 3 antibody; SDPIII antibody; SH3 domain containing protein 6511 antibody; SH3 domain-containing protein 6511 antibody; syndapin III antibody
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宿主：
Rabbit
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反應(yīng)種屬：
Human
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免疫原：
Recombinant Human Protein kinase C and casein kinase substrate in neurons protein 3 protein (1-300AA)
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免疫原種屬：
Homo sapiens (Human)
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標(biāo)記方式：
FITC
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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產(chǎn)品提供形式：
Liquid
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儲(chǔ)存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能：
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
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基因功能參考文獻(xiàn)：
- Show that in neuroendocrine chromaffin cells fusion pore expansion and catecholamine release are limited specifically by mutation of syndapin 3. PMID: 24500282
- Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules PMID: 22573331
- PACSIN3 has a novel function as an up-regulator in the signaling of proHB-EGF shedding induced by TPA and angiotensin II PMID: 12952982
- PACSIN 3 acts as an auxiliary protein of TRPV4 channel that not only affects the channel's subcellular localization but also modulates its function in a stimulus-specific manner. PMID: 18174177
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亞細(xì)胞定位：
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
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蛋白家族：
PACSIN family
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組織特異性：
Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney.
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數(shù)據(jù)庫鏈接：
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