P4hb Antibody, HRP conjugated
-
中文名稱(chēng)：P4hb兔多克隆抗體, HRP偶聯(lián)
-
貨號(hào)：CSB-PA017342YB01MO
-
規(guī)格：￥880
-
其他：
產(chǎn)品詳情
-
產(chǎn)品名稱(chēng)：Rabbit anti-Mus musculus (Mouse) P4hb Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
別名：P4hb antibody; Pdia1Protein disulfide-isomerase antibody; PDI antibody; EC 5.3.4.1 antibody; Cellular thyroid hormone-binding protein antibody; Endoplasmic reticulum resident protein 59 antibody; ER protein 59 antibody; ERp59 antibody; Prolyl 4-hydroxylase subunit beta antibody; p55 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Mouse
-
免疫原：Recombinant Mouse Protein disulfide-isomerase protein (20-509AA)
-
免疫原種屬：Mus musculus (Mouse)
-
標(biāo)記方式：HRP
-
克隆類(lèi)型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA
-
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
-
基因功能參考文獻(xiàn)：
- Unfolded protein response caused by protein misfolding, may lead to PDI-dependent NOX activation and contribute to neurotoxicity in neurodegenerative diseases including ALS. PMID: 23118353
- PDI from endothelial cells is required for fibrin generation in vivo. PMID: 20668226
- Protein disulfide isomerase (PDI) on the platelet surface is recognized by anti-dengue virus NS1 antibodies. PMID: 19822367
-
亞細(xì)胞定位：Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome. Cell membrane; Peripheral membrane protein.
-
蛋白家族：Protein disulfide isomerase family
-
數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-
