NUP85 Antibody, FITC conjugated
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中文名稱：NUP85兔多克隆抗體, FITC偶聯
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貨號：CSB-PA874821LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) NUP85 Polyclonal antibody
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Uniprot No.：
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基因名：NUP85
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別名：85 kDa nucleoporin antibody; FLJ12549 antibody; FROUNT antibody; Frount protein antibody; Nuclear pore complex protein nucleoporin 85 kDa antibody; nuclear pore complex protein nucleoporin Nup75 antibody; Nuclear pore complex protein Nup85 antibody; Nucleoporin 85 antibody; Nucleoporin 85kDa antibody; Nucleoporin nucleoporin 85kDa antibody; Nucleoporin Nup75 antibody; Nucleoporin NUP85 antibody; nucleoporin, 75-KD antibody; Nucleoporin85 antibody; Nup 75 antibody; NUP 85 antibody; Nup75 antibody; nup85 antibody; NUP85_HUMAN antibody; PCN antibody; PCNT 1 antibody; PCNT antibody; PCNT, formerly antibody; PCNT1 antibody; Pericentrin antibody; Pericentrin, formerly antibody; Pericentrin-1 antibody; Pericentrin1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Nuclear pore complex protein Nup85 protein (201-500AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP96/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade. Involved in nephrogenesis.
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基因功能參考文獻：
- results support a model of CCR2 equilibrium: chemokine binding changes the conformational equilibrium of CCR2 toward the active state, and Pro-C switches its binding partner from the membrane to FROUNT PMID: 25283965
- Residues on the hydrophobic side are completely conserved among FROUNT-binding receptors. PMID: 24128342
- Data show that the C Terminus of Nup120 Directly Binds Nup145C and Nup85. PMID: 19576787
- The CCL2/CCR2 pathway via FROUNT may influence the clinical severity of CHF. PMID: 17395051
- FROUNT binds to the C-terminal domain of CCR5 in addition to that of CCR2. PMID: 19841162
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亞細胞定位：Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Nucleus membrane.
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蛋白家族：Nucleoporin Nup85 family
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數據庫鏈接：
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