NFYC Antibody
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中文名稱：NFYC兔多克隆抗體
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貨號(hào)：CSB-PA015775GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：CAAT box DNA binding protein subunit C antibody; CAAT box DNA-binding protein subunit C antibody; CBF C antibody; CBFC antibody; CCAAT binding factor subunit C antibody; CCAAT transcription binding factor subunit gamma antibody; DKFZp667G242 antibody; FLJ45775 antibody; H1TF2A antibody; HAP5 antibody; histone H1 transcription factor large subunit 2A antibody; HSM antibody; NF-YC antibody; NFYC antibody; NFYC_HUMAN antibody; Nuclear transcription factor Y gamma antibody; Nuclear transcription factor Y subunit C antibody; Nuclear transcription factor Y subunit gamma antibody; OTTHUMP00000009207 antibody; OTTHUMP00000009208 antibody; OTTHUMP00000009209 antibody; OTTHUMP00000009210 antibody; OTTHUMP00000009211 antibody; OTTHUMP00000009212 antibody; OTTHUMP00000009213 antibody; OTTHUMP00000009215 antibody; OTTHUMP00000009217 antibody; OTTHUMP00000231028 antibody; Transactivator HSM 1/2 antibody; transactivator HSM-1 antibody; Transactivator HSM-1/2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human NFYC
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
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基因功能參考文獻(xiàn)：
- NF-YC was significantly increased in gliomas. Knockdown of NF-YC reduced brain tumor size in vivo. NF-YC played as an independent predictor of patient survival. PMID: 27495011
- p53 negatively regulates the expression of the PRR11-SKA2 bidirectional transcription unit through NF-Y, suggesting that the inability to repress the PRR11-SKA2 bidirectional transcription unit after loss of p53 might contribute to tumorigenesis. PMID: 28257042
- TAF12 and NFYC are transcription factors that regulate the epigenome, whereas RAD54L plays a central role in DNA repair PMID: 25965574
- the expression of the adipogenic differentiation genes fatty acid binding protein-4, adiponectin, and leptin and the formation of fat droplets were impaired. PMID: 23657974
- NFY-C expression was elevated in colorectal adenocarcinomas; moreover, NFY-C mRNA levels correlated with time to disease progression, while NFY-C protein expression was significantly higher in metastatic disease PMID: 22104449
- Sp1, NF-Y and FOXO transcription factors are involved in the regulation of LKB1 transcription. PMID: 22412893
- NF-YC functions as a new corepressor of agonist-bound mineralocorticoid receptor via alteration of aldosterone-induced MR conformation PMID: 20054001
- role in repressing Smad2 and Smad3 transactivating activity PMID: 12023901
- C/EBPbeta contributes to the induction of hepatocyte replication in response to HGF in rodents, which is likely due to post-translational modifications. PMID: 15922473
- Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple neoplasms. PMID: 19559782
- NF-YC complexity is generated by dual promoters and alternative splicing PMID: 19690168
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亞細(xì)胞定位：Nucleus.
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蛋白家族：NFYC/HAP5 subunit family
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數(shù)據(jù)庫(kù)鏈接：
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