Ms4a1 Antibody

中文名稱：

Ms4a1兔多克隆抗體
貨號：

CSB-PA015007LA01MO
規格：

￥440
圖片：
Western blot
All lanes: Ms4a1 antibody at 4µg/ml
Lane 1: Hela whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: 293T whole cell lysate
Lane 4: HL60 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 32 kDa
Observed band size: 32 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Ms4a1 Polyclonal antibody
Uniprot No.：

P19437
基因名：

Ms4a1
別名：

Ms4a1 antibody; Cd20 antibody; Ly-44 antibody; Ms4a2 antibody; B-lymphocyte antigen CD20 antibody; B-cell differentiation antigen Ly-44 antibody; Lymphocyte antigen 44 antibody; Membrane-spanning 4-domains subfamily A member 1 antibody; CD antigen CD20 antibody
宿主：

Rabbit
反應種屬：

Mouse, Human
免疫原：

Recombinant Mouse B-lymphocyte antigen CD20 protein (111-291AA)
免疫原種屬：

Mus musculus (Mouse)

標記方式：

Non-conjugated

本頁面中的產品，Ms4a1 Antibody (CSB-PA015007LA01MO)，的標記方式是Non-conjugated。對于Ms4a1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA015007LB01MO	Ms4a1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA015007LC01MO	Ms4a1 Antibody, FITC conjugated
Biotin	CSB-PA015007LD01MO	Ms4a1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
基因功能參考文獻：
1. Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment PMID: 28533311
2. Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model PMID: 26888257
3. Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy. PMID: 26261496
4. this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity. PMID: 23966626
5. CD20 is required for store-operated calcium entry in C2C12 myoblasts. PMID: 22982241
6. immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells. PMID: 20189250
7. type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling PMID: 20354182
8. CD20 deficiency in humans results in impaired T cell-independent antibody responses. PMID: 20038800
9. review of structure, function, tissue and cell distribution PMID: 12144126
10. Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression. PMID: 15210744
11. expression in bacterial cells; isolation and biophysical and structural studies PMID: 16285718
12. In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice PMID: 18354225
13. involvement of CD20 in calcium influx PMID: 18474602
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亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
蛋白家族：

MS4A family
數據庫鏈接：

KEGG: mmu:12482

STRING: 10090.ENSMUSP00000126422

UniGene: Mm.4046

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