MOCOS Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q96EN8
基因名：

MOCOS
別名：

MOCOS antibody; Molybdenum cofactor sulfurase antibody; MCS antibody; MOS antibody; MoCo sulfurase antibody; hMCS antibody; EC 2.8.1.9 antibody; Molybdenum cofactor sulfurtransferase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human MOCOS
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime.
基因功能參考文獻：
1. MOCOS sulfurates the molybdenum cofactor of xanthine oxidase (XDH) and aldehyde oxidase 1 (AOX1), which is required for their activities. PMID: 22495427
2. Two mutations, both in the N-terminal domain of the Human Molybdenum Cofactor Sulfurase (HMCS), were reported in patients with type II xanthinuria. PMID: 17368066
相關(guān)疾病：

Xanthinuria 2 (XAN2)
蛋白家族：

Class-V pyridoxal-phosphate-dependent aminotransferase family, MOCOS subfamily
數(shù)據(jù)庫鏈接：

HGNC: 18234

OMIM: 603592

KEGG: hsa:55034

STRING: 9606.ENSP00000261326

UniGene: Hs.405028

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