MATN2 Antibody

中文名稱：

MATN2兔多克隆抗體
貨號：

CSB-PA013521LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA013521LA01HU diluted at 1:200 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) MATN2 Polyclonal antibody
Uniprot No.：

O00339
基因名：

MATN2
別名：

Crtm2 antibody; MATN 2 antibody; Matn2 antibody; MATN2_HUMAN antibody; Matrilin-2 antibody; Matrilin2 antibody; MGC102477 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Matrilin-2 protein (746-867AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，MATN2 Antibody (CSB-PA013521LA01HU)，的標記方式是Non-conjugated。對于MATN2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA013521LB01HU	MATN2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013521LC01HU	MATN2 Antibody, FITC conjugated
Biotin	CSB-PA013521LD01HU	MATN2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in matrix assembly.
基因功能參考文獻：
1. findings showed that YopK binds to the cell surface-exposed endogenous MATN2 and that purified YopK protein strongly inhibits the bacterial adherence to HeLa cells PMID: 28533472
2. Data show that the mRNA and protein levels of matrilin-2 were increased after irradiation treatment in both mouse lung tissue and human pulmonary alveolar epithelial cells (HPAEpiC). PMID: 27923659
3. Taken together, our results showed that high-glucose-induced Matrilin-2 expression that was mediated by the TGF-beta1/Smad3 signaling pathway might play a role in Diabetic nephropathy (DN) pathogenesis and our finding provided a potential diagnostic and/or therapeutic target for DN. PMID: 27105914
4. Matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal, partly through a TLR4-mediated mechanism PMID: 26271809
5. matrilin-2, a filament-forming protein widely distributed in extracellular matrices. PMID: 11852232
6. matrilin-2 is expressed in normal skin by keratinocytes and fibroblasts and may thus contribute to cutaneous homeostasis. PMID: 12164922
7. study of interactions by which matrilin-2 can be integrated into extracellular filamentous networks PMID: 12180907
8. These results suggest that matrilin-2 may be a specific and clinically useful biomarker for discriminating between indolent and clinically aggressive pilocytic astrocytoma. PMID: 16401863
9. DeltaNp63/BMP-7 signaling pathway modulates wound healing process through the regulation of matrilin-2. PMID: 18328806
10. data indicate matrilin-2 is a novel basement membrane component in the liver, synthesized during sinusoidal "capillarization" in cirrhosis & in hepatocellular carcinoma PMID: 18386166
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亞細胞定位：

Secreted.
數據庫鏈接：

HGNC: 6908

OMIM: 602108

KEGG: hsa:4147

STRING: 9606.ENSP00000430487

UniGene: Hs.189445

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