MATN2 Antibody, HRP conjugated

說明書

中文名稱：

MATN2兔多克隆抗體, HRP偶聯(lián)
貨號(hào)：

CSB-PA013521LB01HU
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MATN2 Polyclonal antibody
Uniprot No.：

O00339
基因名：

MATN2
別名：

Crtm2 antibody; MATN 2 antibody; Matn2 antibody; MATN2_HUMAN antibody; Matrilin-2 antibody; Matrilin2 antibody; MGC102477 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Matrilin-2 protein (746-867AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Involved in matrix assembly.
基因功能參考文獻(xiàn)：
1. findings showed that YopK binds to the cell surface-exposed endogenous MATN2 and that purified YopK protein strongly inhibits the bacterial adherence to HeLa cells PMID: 28533472
2. Data show that the mRNA and protein levels of matrilin-2 were increased after irradiation treatment in both mouse lung tissue and human pulmonary alveolar epithelial cells (HPAEpiC). PMID: 27923659
3. Taken together, our results showed that high-glucose-induced Matrilin-2 expression that was mediated by the TGF-beta1/Smad3 signaling pathway might play a role in Diabetic nephropathy (DN) pathogenesis and our finding provided a potential diagnostic and/or therapeutic target for DN. PMID: 27105914
4. Matrilin-2 induces post-burn inflammatory responses as an endogenous danger signal, partly through a TLR4-mediated mechanism PMID: 26271809
5. matrilin-2, a filament-forming protein widely distributed in extracellular matrices. PMID: 11852232
6. matrilin-2 is expressed in normal skin by keratinocytes and fibroblasts and may thus contribute to cutaneous homeostasis. PMID: 12164922
7. study of interactions by which matrilin-2 can be integrated into extracellular filamentous networks PMID: 12180907
8. These results suggest that matrilin-2 may be a specific and clinically useful biomarker for discriminating between indolent and clinically aggressive pilocytic astrocytoma. PMID: 16401863
9. DeltaNp63/BMP-7 signaling pathway modulates wound healing process through the regulation of matrilin-2. PMID: 18328806
10. data indicate matrilin-2 is a novel basement membrane component in the liver, synthesized during sinusoidal "capillarization" in cirrhosis & in hepatocellular carcinoma PMID: 18386166
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亞細(xì)胞定位：

Secreted.
數(shù)據(jù)庫鏈接：

HGNC: 6908

OMIM: 602108

KEGG: hsa:4147

STRING: 9606.ENSP00000430487

UniGene: Hs.189445

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