LHPP Antibody, FITC conjugated
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中文名稱：LHPP兔多克隆抗體, FITC偶聯
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貨號：CSB-PA867114HC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) LHPP Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：FLJ44846 antibody; FLJ46044 antibody; HDHD2B antibody; hLHPP antibody; lhpp antibody; LHPP_HUMAN antibody; Phospholysine phosphohistidine inorganic pyrophosphate phosphatase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein (1-270AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
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基因功能參考文獻：
- LHPP suppresses cell proliferation and metastasis in cervical cancer, and promotes apoptosis by suppressing AKT activation. PMID: 29944886
- in patients with hepatocellular carcinoma, low expression of LHPP correlated with increased tumour severity and reduced overall survival; thus LHPP is a protein histidine phosphatase and tumour suppressor, suggesting that deregulated histidine phosphorylation is oncogenic PMID: 29562234
- LHPP is associated with the interplay of risky sexual behaviors and alcohol dependence. PMID: 27531626
- Patients with major depressive disorder with LHPP rs35936514 CT/TT genotype have increased activity in certain brain regions. PMID: 27843651
- LHPP gene variation is associated with oral cavity and pharyngeal cancer. PMID: 27749845
- Lhpp or a product of a collinear brain-specific transcript, therefore, may interact with Htr1a in the pathogenesis of major depression PMID: 18268499
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：HAD-like hydrolase superfamily
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組織特異性：Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain.
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數據庫鏈接：
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