KHDRBS2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) KHDRBS2 Polyclonal antibody
Uniprot No.：

Q5VWX1
基因名：

KHDRBS2
別名：

KH domain containing; RNA binding; signal transduction associated protein 2 antibody; 6330586C16Rik antibody; bA535F17.1 antibody; FLJ38664 antibody; hSLM 1 antibody; hSLM-1 antibody; KH domain containing; RNA binding; signal transduction associated 2 antibody; KH domain-containing antibody; KHDR2_HUMAN antibody; khdrbs2 antibody; MGC26664 antibody; RNA-binding antibody; Sam68 like mammalian protein 1 antibody; Sam68-like mammalian protein 1 antibody; signal transduction-associated protein 2 antibody; SLM 1 antibody; SLM-1 antibody; SLM1 antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，KHDRBS2 Antibody (CSB-PA730139LA01HU)，的標記方式是Non-conjugated。對于KHDRBS2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA730139LB01HU	KHDRBS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA730139LC01HU	KHDRBS2 Antibody, FITC conjugated
Biotin	CSB-PA730139LD01HU	KHDRBS2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
基因功能參考文獻：
1. molecular cloning and characterization PMID: 12549823
亞細胞定位：

Nucleus.
蛋白家族：

KHDRBS family
組織特異性：

Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
數據庫鏈接：

HGNC: 18114

OMIM: 610487

KEGG: hsa:202559

STRING: 9606.ENSP00000281156

UniGene: Hs.519794

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