IMPG2 Antibody

中文名稱：

IMPG2兔多克隆抗體
貨號：

CSB-PA011704LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of Hela cells with CSB-PA011704LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) IMPG2 Polyclonal antibody
Uniprot No.：

Q9BZV3
基因名：

IMPG2
別名：

IMPG2 antibody; IPM200 antibody; Interphotoreceptor matrix proteoglycan 2 antibody; Interphotoreceptor matrix proteoglycan of 200 kDa antibody; IPM 200 antibody; Sialoprotein associated with cones and rods proteoglycan antibody; Spacrcan antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Interphotoreceptor matrix proteoglycan 2 protein (616-759AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，IMPG2 Antibody (CSB-PA011704LA01HU)，的標記方式是Non-conjugated。對于IMPG2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA011704LB01HU	IMPG2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA011704LC01HU	IMPG2 Antibody, FITC conjugated
Biotin	CSB-PA011704LD01HU	IMPG2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.
基因功能參考文獻：
1. IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families. PMID: 25085631
2. Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life. PMID: 24876279
3. identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa PMID: 20673862
4. IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival PMID: 10542133
相關疾病：

Retinitis pigmentosa 56 (RP56); Macular dystrophy, vitelliform, 5 (VMD5)
亞細胞定位：

Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
組織特異性：

Expressed in the retina (at protein level). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and t
數據庫鏈接：

HGNC: 18362

OMIM: 607056

KEGG: hsa:50939

STRING: 9606.ENSP00000193391

UniGene: Hs.209249

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