HGD Antibody
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中文名稱：HGD兔多克隆抗體
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貨號：CSB-PA842354ESR2HU
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規(guī)格：￥3900
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圖片：
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Western blot
All lanes: HGDantibody at 2.43μg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa -
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA842354ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA842354ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) HGD Polyclonal antibody
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Uniprot No.：
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基因名：HGD
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別名：2-dioxygenase antibody; AKU antibody; FLJ94126 antibody; hgd antibody; HGD_HUMAN antibody; HGO antibody; Homogentisate 1 2 dioxygenase antibody; Homogentisate 1 antibody; Homogentisate oxidase antibody; Homogentisate oxygenase antibody; Homogentisic acid oxidase antibody; Homogentisicase antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Homogentisate 1,2-dioxygenase protein (226-445AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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基因功能參考文獻：
- Twelve novel HGD gene variants have been identified in 99 alkaptonuria patients affecting the bones. PMID: 25804398
- A novel alkaptonuria mutation, c.87 + 1G > A, shows a significant founder effect and high prevalence in a nomadic Indian population. PMID: 24575791
- study described two novel HGD mutations in a Chinese alkaptonuria family, the splicing mutation of IVS7 1G>C, a donor splice site of exon 7, and a missense mutation of F329C in exon 12 PMID: 23353776
- Report mutations of the HGD gene in Jordanian alkaptonuria patients. PMID: 21437689
- The observed increase of HGD expression in Alkaptonuria cells is probably due to a compensatory mechanism to overcome the almost null catalytic activity of the deficient enzyme PMID: 22105303
- An update on molecular genetics of Alkaptonuria (AKU).(review) PMID: 21720873
- Familiar ochronotic arthropathy is caused by a gene mutation of the homogentisic acid 1,2-dioxygenase (HGD) gene traced three hundred years in a Hungarian family. PMID: 20462779
- A comprehensive mutation analysis of 93 patients enrolled in this study, as well as an extensive update of all previously published HGD mutations associated with alkaptonuria, is reported. PMID: 19862842
- Turkish mutation shares an homogentisate 1,2-dioxygenase haplotype with the mutation found in Finland, Slovakia and India, suggesting that R58fs is an old alkaptonuria mutation that probably originated in central Asia PMID: 12872836
- Four different mutations of the HGD gene were found in alkaptonuria and ochronotic arthropathy diagnoses. PMID: 16085442
- A single nucleotide deletion located in exon 3 resulted in a frameshift mutation in HGD gene in family with alkaptonuria. PMID: 18945288
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相關疾病：Alkaptonuria (AKU)
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蛋白家族：Homogentisate dioxygenase family
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組織特異性：Highest expression in the prostate, small intestine, colon, kidney and liver.
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數據庫鏈接：
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