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中文名稱：
GFRA4兔多克隆抗體
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貨號(hào)：
CSB-PA271998
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規(guī)格：
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：
GDNF family receptor alpha 4 antibody; GDNF family receptor alpha-4 antibody; GDNF receptor alpha-4 antibody; GDNFR-alpha-4 antibody; GFR alpha 4 antibody; GFR receptor alpha 4 antibody; GFR-alpha-4 antibody; GFRA4 antibody; GFRA4_HUMAN antibody; Glial cell line derived neurotrophic factor family receptor alpha 4 antibody; Neurotrophic factor receptor splice variant A (Gfra4 gene) antibody; OTTHUMP00000030106 antibody; OTTHUMP00000030107 antibody; Persephin receptor antibody
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宿主：
Rabbit
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反應(yīng)種屬：
Human
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免疫原：
Synthetic peptide of Human GFRA4
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免疫原種屬：
Homo sapiens (Human)
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標(biāo)記方式：
Non-conjugated
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抗體亞型：
IgG
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純化方式：
Antigen affinity purification
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：
Liquid
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應(yīng)用范圍：
ELISA,IHC
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推薦稀釋比：
| Application |
Recommended Dilution |
| ELISA |
1:1000-1:5000 |
| IHC |
1:25-1:100 |
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Protocols：
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儲(chǔ)存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點(diǎn)詳情
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功能：
Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
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基因功能參考文獻(xiàn)：
- Results support that aberrant CpG hypermethylation at least partly accounts for GFRA4 silencing in HSCR, which impairs its protective role in enteric nervous system. PMID: 29634418
- High GFRA4 expression is associated with Hirschsprung's Disease. PMID: 29090971
- GDNF/GFRalpha1 is crucial for efficient signal transduction to recruit Ret protein into lipid rafts. PMID: 15225646
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亞細(xì)胞定位：
[Isoform GFRalpha4a]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4b]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4c]: Secreted.
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蛋白家族：
GDNFR family
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組織特異性：
Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands.
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數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA271998(GFRA4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
