GADL1 Antibody

說明書

產品詳情

Uniprot No.：

Q6ZQY3
基因名：

GADL1
別名：

GADL1Acidic amino acid decarboxylase GADL1 antibody; Aspartate 1-decarboxylase antibody; ADC antibody; HuADC antibody; EC 4.1.1.11 antibody; Cysteine sulfinic acid decarboxylase antibody; CSADC antibody; HuCSADC antibody; EC 4.1.1.29 antibody; Glutamate decarboxylase-like protein 1 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human GADL1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate.
基因功能參考文獻：
1. No difference in GADL1 expression was observed among lymphoblastoid cells from excellent-responders, non-responders or controls. Furthermore, lithium did not induce significant changes in GADL1 expression levels after 4 or 8 days. These results did not support an association of GADL1 expression in the determination of a lithium response in BD patients. PMID: 28214779
2. taurine biosynthesis in vertebrates involves two structurally related PLP-dependent decarboxylases (cysteine sulfinic acid decarboxylase and glutamic acid decarboxylase like 1) PMID: 26327310
3. The study did not identify a major relationship between the GADL1 polymorphisms and lithium response in an Indian population. PMID: 25415457
4. Genetic variations in GADL1 are associated with the response to lithium maintenance treatment for bipolar I disorder in patients of Han Chinese descent. PMID: 24369049
蛋白家族：

Group II decarboxylase family
組織特異性：

Expressed very weakly in neurons and not detected in astrocytes, brain or liver.
數據庫鏈接：

HGNC: 27949

OMIM: 615601

KEGG: hsa:339896

STRING: 9606.ENSP00000282538

UniGene: Hs.657052

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