FOXH1 Antibody, Biotin conjugated
-
中文名稱：FOXH1兔多克隆抗體, Biotin偶聯
-
貨號：CSB-PA008817LD01HU
-
規格：￥880
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) FOXH1 Polyclonal antibody
-
Uniprot No.：
-
基因名：FOXH1
-
別名：FAST 1 antibody; Fast 2 antibody; Fast-1 antibody; Fast-2 antibody; FAST1 antibody; Fast2 antibody; Forkhead activin signal transducer 1 antibody; Forkhead activin signal transducer 2 antibody; Forkhead box H1 antibody; Forkhead box protein H1 antibody; FOX H1 antibody; FOXH 1 antibody; FOXH1 antibody; FOXH1_HUMAN antibody; hFAST 1 antibody; hFAST-1 antibody; hFAST1 antibody; Human homolog of Xenopus forkhead activin signal transducer 1 antibody; TGF beta/Activin signal transducer FAST1 antibody
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Forkhead box protein H1 protein (153-269AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Biotin
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：>95%, Protein G purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
-
應用范圍：ELISA
-
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
-
基因功能參考文獻：
- These results indicate that Smad4 acts as a tumor suppressor by activating FOXH1, and then suppressing the expression of estrogen receptor, in addition to tumor migration and invasion. PMID: 25482028
- HEB and E2A-bind the SCA motif at regions overlapping SMAD2/3 and FOXH1 PMID: 21828274
- Four genetic variants are found in FOXH1 that are associated with ventricular septal defects in Chinese patients. PMID: 19525021
- Results suggest that PKA can negatively regulate ERalpha, at least in part, through FoxH1. PMID: 19711044
- This work suggests that FAST-1 may participate in the vascular smooth muscle response to injury and may represent a potential molecular target for modulating the progression of cardiac allograft vasculopathy. PMID: 15737749
- Smad-binding peptide aptamer FOXH1 can be developed to selectively inhibit TGF-beta-induced gene expression. PMID: 15750622
- These results demonstrate for a functional role for TGF-beta ligands in regulation of mammalian Mixl1, identify FoxH1 as an essential co-activator, and implicate Nodal as the embryonic regulator of Mixl1 in mesendoderm morphogenesis. PMID: 15982639
- FoxH1 has a role in androgen receptor-mediated transactivation PMID: 16120611
- Reduced NODAL signaling via mutation of several pathway members including FOXH1 is linked to heart defects and holoprosencephaly. PMID: 18538293
顯示更多
收起更多
-
亞細胞定位：Nucleus.
-
組織特異性：Ubiquitous.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
