ECI2 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ECI2 Polyclonal antibody
Uniprot No.：

O75521
基因名：

ECI2
別名：

2-trans-enoyl-CoA isomerase antibody; ACBD2 antibody; acyl Coenzyme A binding domain containing 2 antibody; D2-enoyl-CoA isomerase antibody; D3 antibody; D3 D2 enoyl CoA isomerase antibody; DBI related protein 1 antibody; DBI-related protein 1 antibody; delta(2)-enoyl-CoA isomerase antibody; Delta(3) antibody; Delta(3) delta(2) enoyl CoA isomerase antibody; Diazepam-binding inhibitor-related protein 1 antibody; Dodecenoyl CoA isomerase antibody; Dodecenoyl-CoA isomerase antibody; DRS 1 antibody; DRS-1 antibody; DRS1 antibody; Eci2 antibody; ECI2_HUMAN antibody; Enoyl-CoA delta isomerase 2 antibody; HCA88 antibody; Hepatocellular carcinoma associated antigen 88 antibody; Hepatocellular carcinoma-associated antigen 88 antibody; mitochondrial antibody; pECI antibody; Peroxisomal 3 antibody; Peroxisomal 3,2-trans-enoyl-CoA isomerase antibody; Peroxisomal D3 D2 enoyl CoA isomerase antibody; Renal carcinoma antigen NY REN 1 antibody; Renal carcinoma antigen NY-REN-1 antibody
宿主：

Rabbit
反應種屬：

Human, Rat, Mouse
免疫原：

Recombinant Human Enoyl-CoA delta isomerase 2, mitochondrial protein (119-219AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ECI2 Antibody (CSB-PA527983LA01HU)，的標記方式是Non-conjugated。對于ECI2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA527983LB01HU	ECI2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA527983LC01HU	ECI2 Antibody, FITC conjugated
Biotin	CSB-PA527983LD01HU	ECI2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.
基因功能參考文獻：
1. Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival PMID: 28415728
2. Ectopic expression of the ACBD2/ECI2 isoform A in MA-10 cells led to increased basal and hormone-stimulated steroid formation, indicating that ACBD2/ECI2-mediated peroxisomes-mitochondria interactions favor in the exchange of metabolites and/or macromolecules between these 2 organelles in support of steroid biosynthesis. Considering the widespread occurrence of the ACBD2/ECI2 protein, we propose that this protein might se PMID: 27167610
3. Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse PMID: 11916962
4. DRS-1 may serve as an autoantigen eliciting immune attack against hematopoietic stem cells in a subset of acquired aplastic anemia patients characterized by increased paroxysmal nocturnal hemoglobinuria-type cells PMID: 15217832
亞細胞定位：

[Isoform 1]: Mitochondrion.; [Isoform 2]: Peroxisome matrix.
蛋白家族：

Enoyl-CoA hydratase/isomerase family
組織特異性：

Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
數據庫鏈接：

HGNC: 14601

OMIM: 608024

KEGG: hsa:10455

STRING: 9606.ENSP00000369461

UniGene: Hs.15250

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