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DEUP1 Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody
Uniprot No.：

Q05D60
基因名：

DEUP1
別名：

DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
基因功能參考文獻：
1. Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
2. Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
3. suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074
亞細胞定位：

Cytoplasm.
蛋白家族：

CEP63 family
數據庫鏈接：

HGNC: 26344

KEGG: hsa:159989

STRING: 9606.ENSP00000298050

UniGene: Hs.436625

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