DEUP1 Antibody

中文名稱：

DEUP1兔多克隆抗體
貨號：

CSB-PA004729LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA004729LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody
Uniprot No.：

Q05D60
基因名：

DEUP1
別名：

DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DEUP1 Antibody (CSB-PA004729LA01HU)，的標記方式是Non-conjugated。對于DEUP1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA004729LB01HU	DEUP1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004729LC01HU	DEUP1 Antibody, FITC conjugated
Biotin	CSB-PA004729LD01HU	DEUP1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
基因功能參考文獻：
1. Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
2. Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
3. suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074
亞細胞定位：

Cytoplasm.
蛋白家族：

CEP63 family
數據庫鏈接：

HGNC: 26344

KEGG: hsa:159989

STRING: 9606.ENSP00000298050

UniGene: Hs.436625

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