Cd82 Antibody, FITC conjugated
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中文名稱：Cd82兔多克隆抗體, FITC偶聯(lián)
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貨號(hào)：CSB-PA004961LC01MO
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Mus musculus (Mouse) Cd82 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Cd82 antibody; Kai1CD82 antigen antibody; C33 antigen antibody; IA4 antibody; Inducible membrane protein R2 antibody; Metastasis suppressor Kangai-1 homolog antibody; CD antigen CD82 antibody
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宿主：Rabbit
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反應(yīng)種屬：Mouse
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免疫原：Recombinant Mouse CD82 antigen protein (111-227AA)
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免疫原種屬：Mus musculus (Mouse)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
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基因功能參考文獻(xiàn)：
- The CD82 is a functional surface marker of long-term repopulating hematopoietic stem cells (LT-HSCs) that maintains quiescence through interaction with DARC-expressing macrophages in the bone marrow stem cell niche. PMID: 26996598
- Loss of Kai1 expression is associated with neoplasm metastasis. PMID: 23401136
- The synergistic effects of CD82 and GM3 or GM2/GM3 ganglioside on EGFR expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF- and HGF-dependent cell motility and migration of Hepa1-6 cells. PMID: 23968914
- the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes. PMID: 21149584
- KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase PMID: 20089858
- Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation. PMID: 20123085
- An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression. PMID: 16372335
- gp78 promotes sarcoma metastasis by targeting KAI1 for degradation PMID: 18037895
- The transgenic adenocarcinoma of mouse prostate model encompasses androgen depletion independent sublines with increased tumorigenicity and invasiveness. All showed downregulation in tumor suppressor, E-cadherin, and metastatis suppressor, KAI-1. PMID: 18247402
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亞細(xì)胞定位：Cell membrane; Multi-pass membrane protein.
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蛋白家族：Tetraspanin (TM4SF) family
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組織特異性：Highest expression in the spleen and the kidney. Low expression in skeletal muscle and in the heart.
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數(shù)據(jù)庫(kù)鏈接：
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