CRNN Antibody
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中文名稱：CRNN兔多克隆抗體
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貨號：CSB-PA005988GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：CRNN
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別名：53 kDa putative calcium binding protein antibody; 53 kDa putative calcium-binding protein antibody; 53 kDa squamous epithelial induced stress protein antibody; 53 kDa squamous epithelial-induced stress protein antibody; 58 kDa heat shock protein antibody; C1orf10 antibody; Chromosome 1 open reading frame 10 antibody; Cornulin antibody; CRNN antibody; CRNN_HUMAN antibody; DRC1 antibody; PDRC1 antibody; SEP53 antibody; Squamous epithelial heat shock protein 53 antibody; Tumor related protein antibody; Tumor-related protein antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Human CRNN
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. Regulates proliferation induced by proinflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways.
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基因功能參考文獻：
- This study showed a significant correlation between LOH/MSI at 1q21.3 with clinical outcomes and that downregulation of CRNN gene could be considered as a prognostic marker of OSCC. PMID: 25846277
- The single-nucleotide polymorphisms of CRNN (rs941934) and RPTN (rs3001978, rs28441202) may contribute to Atopic Dermatitis development, but further studies on a larger group of Atopic Dermatitis patients are needed to verify this assumption. PMID: 28219068
- Loss of CRNN expression correlated with advanced tumor length, greater tumor invasion depth, lymph node metastasis, and poor survival in patients with esophageal squamous cell carcinoma. PMID: 24263008
- Findings demonstrate that CRNN is a tumor suppressor gene that plays a critical tumor suppressive role in ESCC. PMID: 23894350
- cornulin is an important molecule in normal esophageal pathology and is likely lost during the conversion of normal to neoplastic epithelium PMID: 22560086
- SEP53 may be a component of the mucosal/epithelial innate immune response engaged in an ongoing interaction with a pathogen PMID: 17925851
- Results describe the cloning of porcine SEP53, its homology to the human protein, and its expression in the esophagus and in gastric squamous epithelium. PMID: 18465210
- CRNN mRNA expression is decreased in eczematous skin PMID: 19133922
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亞細胞定位：Cytoplasm. Note=Does not colocalize with TGM1.
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蛋白家族：S100-fused protein family
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組織特異性：Expressed in the basal skin layer (at protein level). Squamous epithelia cell-specific. Expressed in the esophagus (periphery of the cells of the granular and the upper spinous layers), foreskin (granular and lower cornified cells), scalp skin (granular l
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數據庫鏈接：
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