COG6 Antibody
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中文名稱：COG6兔多克隆抗體
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貨號：CSB-PA005710GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：COG6
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別名：CDG2L antibody; COD2 antibody; COG complex subunit 6 antibody; COG6 antibody; COG6_HUMAN antibody; Complexed with Dor1p 2 antibody; Component of oligomeric Golgi complex 6 antibody; Conserved oligomeric Golgi complex component 6 antibody; Conserved oligomeric Golgi complex protein 6 antibody; Conserved oligomeric Golgi complex subunit 6 antibody; KIAA1134 antibody; SHNS antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human COG6
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IF
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for normal Golgi function.
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基因功能參考文獻：
- COG6 is a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. PMID: 27193031
- study presents 7 additional patients with 4 novel COG6 mutations; genotype-phenotype correlation can be discerned ranging from deep intronic mutations found in Shaheen syndrome as the mildest form to loss-of-function mutations leading to early lethal congenital disorders of glycosylation phenotypes PMID: 26260076
- The aim of this study was to investigate whether the HCP5, TNIP1, TNFAIP3, SPATA2 and COG6 genes were genetic risk factors for psoriasis in Chinese population. PMID: 25264125
- Our findings implicate COG6 rs9548934C-->T genotypes and circulating miRNA-1 phenotype in modulating the occurrence and major adverse cardiovascular events of coronary artery disease. PMID: 25197382
- Targeted silencing of components of lobe B of the COG complex, namely COG5, COG6, COG7 and COG8, inhibited HIV-1 replication PMID: 25179963
- data implicate COG6 in the pathogenesis of a novel hypohidrotic disorder in humans that is distinct from congenital disorders of glycosylation. PMID: 23606727
- COG6 interaction with SNARE proteins via universal SNARE-binding motif of COG6 is important for Golgi complex intergrity. PMID: 23057818
- COG6 rs9548934C-->T polymorphism is associated with lower risk of premature coronary artery disease, especially in female subjects and subjects with lower serum lipid levels. PMID: 22883088
- COG directly and positively regulates endosome-to-TGN retrograde transport by specific and direct interaction with the t-SNARE Stx6 via its Cog6 subunit. PMID: 21807881
- This paper reports a new congenital disorder caused by mutations in the human COG8 gene and describes the affect this mutation has on the other COG components. PMID: 17331980
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相關疾病：Congenital disorder of glycosylation 2L (CDG2L); Shaheen syndrome (SHNS)
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亞細胞定位：Golgi apparatus membrane; Peripheral membrane protein.
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蛋白家族：COG6 family
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數據庫鏈接：
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