CLEC11A Antibody
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中文名稱：CLEC11A兔多克隆抗體
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貨號：CSB-PA005515GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：CLEC11A
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別名：C type (calcium dependent; carbohydrate recognition domain) lectin; superfamily member 3 antibody; C type lectin domain family 11 member A antibody; C type lectin superfamily member 3 antibody; C-type lectin domain family 11 member A antibody; C-type lectin superfamily member 3 antibody; CLC11_HUMAN antibody; CLEC11A antibody; CLECSF3 antibody; LSLCL antibody; Lymphocyte secreted C type lectin antibody; Lymphocyte secreted C-type lectin antibody; lymphocyte secreted long form of C type lectin antibody; p47 antibody; Stem cell growth factor antibody; stem cell growth factor lymphocyte secreted C type lectin antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human SCGF
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone.
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基因功能參考文獻：
- Clec11a maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts. PMID: 27976999
- Data show that asymptomatic patients with unstable plaques exhibited higher levels of endothelial microparticles (EMPs), CXCL9 chemokine and stem cell growth factor; lymphocyte secreted C-type lectin (SCGF-beta) compared to those with stable plaques. PMID: 26564003
- level of expression correlates with pain response in subjects with intervertebral disc disorders PMID: 26440592
- This is the first report of SCGF beta in heart failure patients. PMID: 23357302
- These studies highlight a possible role of SCGFalpha in imatinib-induced changes of gastrointestinal stromal tumors structure, consistent with a therapeutic response. PMID: 21943129
- The results presented here demonstrate that homozygous T at -539 in the SCGF promoter is associated with elevated SCGF production, enhanced erythropoiesis, and protection against severe malarial anemia. PMID: 19884328
- SCGF is selectively produced by osseous and hematopoietic stromal cells, and can mediate their proliferative activity on primitive hematopoietic progenitor cells. PMID: 11920266
- Results indicate that interleukin-4, together with recombinant human stem cell factor, can induce T cell maturation from cord blood progenitor cells, and that IL-4 increased the expression of FcepsilonRI on fetal liver mast cells. PMID: 14746805
- Human vascular smooth muscle cells express stem cell factor(SCF) and its receptor, c-kit. SCF is released from its membrane-bound form via MMP-9. SCF/c-kit signaling may affect SMC function via an autocrine pathway. PMID: 15234225
- phagocytosis of hemozoin promotes a decrease in SCGF gene products, which may contribute to reduced erythropoiesis in children with severe malarial anemia. PMID: 19528216
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亞細胞定位：Cytoplasm. Secreted.
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組織特異性：Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
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數據庫鏈接：
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