CLEC11A Antibody

說明書

中文名稱：

CLEC11A兔多克隆抗體
貨號：

CSB-PA896480ESR2HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA896480ESR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA896480ESR2HU at dilution of 1:100

Immunofluorescent analysis of HepG2 cells using CSB-PA896480ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CLEC11A Polyclonal antibody
Uniprot No.：

Q9Y240
基因名：

CLEC11A
別名：

C type (calcium dependent; carbohydrate recognition domain) lectin; superfamily member 3 antibody; C type lectin domain family 11 member A antibody; C type lectin superfamily member 3 antibody; C-type lectin domain family 11 member A antibody; C-type lectin superfamily member 3 antibody; CLC11_HUMAN antibody; CLEC11A antibody; CLECSF3 antibody; LSLCL antibody; Lymphocyte secreted C type lectin antibody; Lymphocyte secreted C-type lectin antibody; lymphocyte secreted long form of C type lectin antibody; p47 antibody; Stem cell growth factor antibody; stem cell growth factor lymphocyte secreted C type lectin antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human C-type lectin domain family 11 member A protein (22-323AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone.
基因功能參考文獻：
1. Clec11a maintains the adult skeleton by promoting the differentiation of mesenchymal progenitors into mature osteoblasts. PMID: 27976999
2. Data show that asymptomatic patients with unstable plaques exhibited higher levels of endothelial microparticles (EMPs), CXCL9 chemokine and stem cell growth factor; lymphocyte secreted C-type lectin (SCGF-beta) compared to those with stable plaques. PMID: 26564003
3. level of expression correlates with pain response in subjects with intervertebral disc disorders PMID: 26440592
4. This is the first report of SCGF beta in heart failure patients. PMID: 23357302
5. These studies highlight a possible role of SCGFalpha in imatinib-induced changes of gastrointestinal stromal tumors structure, consistent with a therapeutic response. PMID: 21943129
6. The results presented here demonstrate that homozygous T at -539 in the SCGF promoter is associated with elevated SCGF production, enhanced erythropoiesis, and protection against severe malarial anemia. PMID: 19884328
7. SCGF is selectively produced by osseous and hematopoietic stromal cells, and can mediate their proliferative activity on primitive hematopoietic progenitor cells. PMID: 11920266
8. Results indicate that interleukin-4, together with recombinant human stem cell factor, can induce T cell maturation from cord blood progenitor cells, and that IL-4 increased the expression of FcepsilonRI on fetal liver mast cells. PMID: 14746805
9. Human vascular smooth muscle cells express stem cell factor(SCF) and its receptor, c-kit. SCF is released from its membrane-bound form via MMP-9. SCF/c-kit signaling may affect SMC function via an autocrine pathway. PMID: 15234225
10. phagocytosis of hemozoin promotes a decrease in SCGF gene products, which may contribute to reduced erythropoiesis in children with severe malarial anemia. PMID: 19528216
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亞細胞定位：

Cytoplasm. Secreted.
組織特異性：

Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
數據庫鏈接：

HGNC: 10576

OMIM: 604713

KEGG: hsa:6320

STRING: 9606.ENSP00000250340

UniGene: Hs.512680

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