CEACAM8 Antibody
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中文名稱：CEACAM8兔多克隆抗體
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貨號：CSB-PA077200
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA077200(CEACAM8 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：Carcinoembryonic antigen CGM6 antibody; Carcinoembryonic antigen gene family member 6 antibody; Carcinoembryonic antigen related cell adhesion molecule 8 antibody; Carcinoembryonic antigen-related cell adhesion molecule 8 antibody; CD 66b antibody; CD 67 antibody; CD66b antibody; CD66b antigen antibody; CD67 antibody; CD67 antigen antibody; CEACAM 8 antibody; CEACAM8 antibody; CEAM8_HUMAN antibody; CGM 6 antibody; CGM6 antibody; NCA 95 antibody; NCA95 antibody; Non-specific cross-reacting antigen NCA-95 antibody; Nonspecific cross reacting antigen NCA 95 antibody; Nonspecific cross reacting antigen NCA95 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Fusion protein of Human CEACAM8
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
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基因功能參考文獻：
- Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. PMID: 27863478
- Data suggest ways in which carcinoembryonic antigen-related cell adhesion molecules CEACAM6 and CEACAM8 regulate the biological functions of one another. PMID: 26483485
- Granulocytes from type 2 diabetes patients display higher granulocyte cell surface expression of CD66b compared with values of healthy controls. PMID: 23686079
- The highly elevated gene expression of CEACAM6 and CEACAM8 in primary myelofibrosis can serve as molecular markers of myelofibrotic transformation. PMID: 21470677
- All the leukemic samples showed overexpression of CEACAM6 and 8 when compared with normal granulocytes. PMID: 17909799
- CD66b molecules are involved in regulating adhesion and activation of eosinophils, possibly through their localization in lipid rafts and interaction with other cell surface molecules, such as CD11b. PMID: 18056392
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亞細胞定位：Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
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蛋白家族：Immunoglobulin superfamily, CEA family
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組織特異性：Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
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數據庫鏈接：
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