CCDC170 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) CCDC170 Polyclonal antibody
Uniprot No.：

Q8IYT3
基因名：

CCDC170
別名：

bA282P11.1 antibody; CC170_HUMAN antibody; CCDC170 antibody; Chromosome 6 open reading frame 97 antibody; Coiled coil domain containing protein C6orf97 antibody; Coiled-coil domain-containing protein 170 antibody; FLJ23305 antibody; Hypothetical protein LOC80129 antibody; LOC80129 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Coiled-coil domain-containing protein 170 protein (574-651AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in Golgi-associated microtubules organization and stabilization.
基因功能參考文獻：
1. Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. PMID: 28687497
2. Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients. PMID: 25370037
3. Our findings suggest that ESR1 and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women. PMID: 24481879
4. ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers PMID: 25099679
5. Variation in rs3757318 of C6orf97 is associated with breast cancer risk. PMID: 25338983
6. SNPs associated with breast cancer differ for Asian, European, and African ancestry groups PMID: 20661439
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亞細胞定位：

Golgi apparatus.
數據庫鏈接：

HGNC: 21177

KEGG: hsa:80129

STRING: 9606.ENSP00000239374

UniGene: Hs.660044

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