C8B Antibody

說明書

中文名稱：

C8B兔多克隆抗體
貨號：

CSB-PA004195ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA004195ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA004195ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) C8B Polyclonal antibody
Uniprot No.：

P07358
基因名：

C8B
別名：

C8b antibody; CO8B_HUMAN antibody; Complement component 8 beta polypeptide antibody; Complement component 8 subunit beta antibody; Complement component C8 beta chain antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Complement component C8 beta chain protein (55-350AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
基因功能參考文獻：
1. The binding specificity between C8 beta and C8 alpha subunits is determined by a cooperative interaction of the N-terminal thrombospondin type 1 module and the membrane attack complex/perforin domain. PMID: 12220191
2. results indicate that the principal binding site for C9 lies within the MACPF domain of C8alpha; they also suggest this site and the binding sites for C8beta and C8gamma are distinct PMID: 16618117
相關疾病：

Complement component 8 deficiency, 2 (C8D2)
亞細胞定位：

Secreted.
蛋白家族：

Complement C6/C7/C8/C9 family
數據庫鏈接：

HGNC: 1353

OMIM: 120960

KEGG: hsa:732

STRING: 9606.ENSP00000360281

UniGene: Hs.391835

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