Ang4 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Mus musculus (Mouse) Ang4 Polyclonal antibody
Uniprot No.：

Q3TMQ6
基因名：

Ang4
別名：

Angiogenin-4 (EC 3.1.27.-), Ang4
宿主：

Rabbit
反應種屬：

Mouse
免疫原：

Recombinant Mouse Angiogenin-4 protein (25-144aa)
免疫原種屬：

Mus musculus (Mouse)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro).
基因功能參考文獻：
1. Intestinal intraepithelial lymphocyte-enterocyte crosstalk regulates production of bactericidal angiogenin 4 by Paneth cells upon microbial challenge. PMID: 24358364
2. The cellular source of mouse Ang4 in the colon following T. muris infection is the goblet cell and expression is under the control of IL-13. PMID: 22970115
3. Expression of Reg3 proteins and Ang4 by goblet cells point to an important role for goblet cells in innate defense. PMID: 22723890
4. differences in gene expression profiles associated with immune and defence responses, including angiogenin 4 PMID: 19852835
5. protein structure of angiogenin 4 PMID: 15772759
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亞細胞定位：

Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus.
蛋白家族：

Pancreatic ribonuclease family
組織特異性：

Detected in small intestine, caecum and colon, with the highest expression in Paneth cells in the intestinal epithelium.
數據庫鏈接：

KEGG: mmu:219033

STRING: 10090.ENSMUSP00000073525

UniGene: Mm.343899

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