APOF Antibody

說明書

產品詳情

Uniprot No.：

Q13790
基因名：

APOF
別名：

Apo-F antibody; Apof antibody; APOF_HUMAN antibody; Apolipoprotein F antibody; DKFZp781G18150 antibody; Lipid transfer inhibitor protein antibody; LTIP antibody; MGC22520 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Human APOF
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.
基因功能參考文獻：
1. Direct interactions between C/EBPalpha and ETS-1 were important for high liver-specific expression of ApoF. PMID: 25726912
2. this study has identified apoF as likely another target gene of FXR. PMID: 24211198
3. LTIP translocation is dependent on LDL lipid composition PMID: 21937674
4. LTIP tailors CETP-mediated remodeling of HDL3 and HDL2 particles in subclass-specific ways, strongly implicating it as a regulator of HDL metabolism PMID: 12907677
5. we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males. PMID: 17901467
6. lipoprotein composition may influence the status of lipid transfer inhibitor protein activity PMID: 18369235
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亞細胞定位：

Secreted.
蛋白家族：

Apolipoprotein F family
組織特異性：

Expressed by the liver and secreted in plasma.
數據庫鏈接：

HGNC: 615

OMIM: 107760

KEGG: hsa:319

STRING: 9606.ENSP00000381250

UniGene: Hs.534302

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