ADAMTS17 Antibody
-
中文名稱：ADAMTS17兔多克隆抗體
-
貨號：CSB-PA007786
-
規格：￥1090
-
其他：
產品詳情
-
Uniprot No.：
-
基因名：ADAMTS17
-
別名：A disintegrin and metalloproteinase with thrombospondin motifs 17 antibody; A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 17 antibody; ADAM metallopeptidase with thrombospondin type 1 motif; 17 antibody; ADAM-TS 17 antibody; ADAM-TS17 antibody; ADAMTS 17 antibody; ADAMTS-17 antibody; ADAMTS17 antibody; ATS17_HUMAN antibody; EC 3.4.24. antibody; FLJ16363 antibody; FLJ32769 antibody; OTTHUMP00000194818 antibody
-
宿主：Rabbit
-
反應種屬：Human,Mouse
-
免疫原：Synthesized peptide derived from the Internal region of Human ADAMTS-17.
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
抗體亞型：IgG
-
純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
-
產品提供形式：Liquid
-
應用范圍：IHC, ELISA
-
推薦稀釋比：
Application Recommended Dilution IHC 1:100-1:300 ELISA 1:20000 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
基因功能參考文獻：
- Secretion of ADAMTS17 requires O-fucosylation. ADAMTS17 binds fibrillin-2 but not fibrillin-1 and does not cleave either. ADAMTS17 regulates fibrillin isoform composition of microfibrils in the eye. PMID: 28176809
- higher Adamts17 expression is found in several human cancer cell subtypes, especially in breast ductal carcinoma and there is an inverse correlation between higher Adamts17 expression and patients' survival. PMID: 24906090
- The mutation in the Weill-Marchesani syndrome (WMS)- gene ADAMTS17 also causes WMS in an Indian family. PMID: 24940034
- A mutation in WMS-like gene ADAMTS17 also causes WMS. PMID: 24940034
- Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition. PMID: 23661674
- Recessive ADAMTS17 mutations are a recurrent cause of isolated spherophakia with short stature. PMID: 22486325
- ADAMTS17 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
- Homozygous mutation in ADAMTS17 causes lenticular myopia, ectopia lentis, glaucoma, spheropakia, and short stature. PMID: 19836009
顯示更多
收起更多
-
相關疾病：Weill-Marchesani-like syndrome (WMSL)
-
亞細胞定位：Secreted, extracellular space, extracellular matrix.
-
組織特異性：Isoform 1 and isoform 2 are expressed at high levels in the lung, brain, whole eye and retina. Isoform 1 shows a weaker expression in the heart, kidney and skeletal muscle. Isoform 2 shows a weaker expression in the kidney, bone marrow and skeletal muscle
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
