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中文名稱：大鼠高半胱氨酸(Hcy)酶聯免疫試劑盒
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貨號：CSB-E13376r
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規格：96T/48T
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價格：￥3900/￥2500
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其他：
產品詳情
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產品描述：大鼠高半胱氨酸(Hcy)酶聯免疫試劑盒（CSB-E13376r）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的Hcy含量。Hcy即同型半胱氨酸，是蛋氨酸代謝的中間產物。其水平升高是心腦血管疾病等多種疾病的獨立危險因素。研究機制上，可能通過損傷血管內皮細胞、促進血栓形成、氧化應激等途徑參與疾病發生發展，對其深入研究有重要臨床意義。試劑盒檢測范圍為0.78 nmol/mL-50 nmol/mL，廣泛應用于大鼠模型的基礎研究，例如在高血壓、動脈粥樣硬化或阿爾茨海默病等動物模型中評估Hcy水平變化，或用于探究營養干預、藥物代謝對Hcy調控的影響，為疾病機制解析及治療策略開發提供可靠數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：N/A
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縮寫：Hcy
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種屬：Rattus norvegicus (Rat)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：0.78 nmol/mL-50 nmol/mL
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靈敏度：0.195 nmol/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Metabolism
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of rat Hcy in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 92 Range % 87-95 1:2 Average % 94 Range % 90-98 1:4 Average % 94 Range % 89-97 1:8 Average % 100 Range % 93-103 -
回收率：
The recovery of rat Hcy spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 95 91-97 EDTA plasma (n=4) 95 92-98 -
標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
nmol/ml OD1 OD2 Average Corrected 50 2.874 2.771 2.823 2.670 25 2.223 2.245 2.234 2.081 12.5 1.418 1.389 1.404 1.251 6.25 0.756 0.775 0.766 0.613 3.12 0.462 0.448 0.455 0.302 1.56 0.321 0.313 0.317 0.164 0.78 0.232 0.225 0.229 0.076 0 0.155 0.151 0.153 -
數據處理：
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貨期：3-5 working days
引用文獻
- Betaine alleviates deficits in motor behavior, neurotoxic effects, and neuroinflammatory responses in a rat model of demyelination AE Essawy, GJ Bekheet, SA Salam, RH Alhasani,Toxicology Reports,2025
- The effect of folic acid supplementation on damage caused by chronic cerebral hypo-perfusion in the hippocampus: the role of antioxidant agents and homocysteine AS Raeini,/,2023
- Prevention of bone deterioration by whole-body vibration in a rat model of pre-type 2 diabetes A Minematsu,Journal of musculoskeletal & neuronal interactions,2023
- Linagliptin and secoisolariciresinol diglucoside attenuate hyperlipidemia and cardiac hypertrophy induced by a high-methionine diet in rats via suppression of hyperhomocysteinemia-induced endoplasmic reticulum stress IA Jalal,Frontiers in pharmacology,2023
- The effects of regular swimming exercise during sodium valproate treatment on seizure behaviors and EEG recordings in pentylenetetrazole-kindled rats S Acar,Epilepsy research,2023
- Impact of folic acid supplementation on ischemia?reperfusion-induced kidney injury in rats: folic acid prophylactic role revisited W Liu,The journal of physiological sciences,2024
- HYPERHOMOCYSTEINEMIA AS A LINK OF CHEMOTHERAPY-RELATED ENDOTHELIUM IMPAIRMENT A Avagimyan,Current Problems in Cardiology,2021
- Nanoemulsification of Rice Bran Wax Policosanol Enhances Its Cardio-protective Effects via Modulation of Hepatic Peroxisome Proliferator-activated Receptor gamma in Hyperlipidemic Rats A Ishaka,Journal of Oleo Science,2020
- DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis H Tao,Archives of Biochemistry and Biophysics,2020
- Folic Acid Decreases Astrocyte Apoptosis by Preventing Oxidative Stress-Induced Telomere Attrition Li W,International Journal of Molecular Sciences,2019
- Nebivolol prevents the increase of asymmetric dimethylarginine and oxidants in hyperhomocysteinemic rats Mustafa Ahmet Huyut, et al,International Journal Of The Cardiovascular Academy,2019
- Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting Zhang Y, et al,Neuroscience Bulletin,2019
- Neuroprotective effect of epigallocatechin-3-gallate (EGCG) on radiation-induced damage and apoptosis in the rat hippocampus Mohamed A. El-Missiry.et al,International Journal of Radiation Biology,2018
- Caffeine Prevents Memory Impairment Induced by Hyperhomocysteinemia Karem H. Alzoubi.et al,Journal of Molecular Neuroscience,2018
- The Effect of Folate Administration on Serum Homocysteine Level and Diabetic Retinopathy Parameters an Experimental Study on Sprague-Dawley rats BANUNDARI RACHMAWATI.et al,/,2018
- Maternal low-quality protein diet exerts sex-specific effects on plasma amino acid profile and alters hepatic expression of methyltransferases in adult rat offspring Akyol A.et al,J Dev Orig Health Dis,2018
- Sodium Arsenite-Induced Learning and Memory Impairment Is Associated with Endoplasmic Reticulum Stress-Mediated Apoptosis in Rat Hippocampus Sun H.et al,Front Mol Neurosci.,2017
- Vascular protective effects of Astragalus membranaceus and its main constituents in rats with chronic hyperhomocysteinemia Li??ong Qiu.et al,Experimental and Therapeutic Medicine,2017
- Orthosiphon stamineus: an Asian tea with substantial anticancer properties Movahedi A.et al,Journal of Nutritional Sciences and Dietetics,2015
- Anti-Hypertensive Effects of Black Raspberry (Rubus occidentalis) in Spontaneously Hypertensive Rats Lee J H.et al,Journal of the Korean Society of Food Science and Nutrition,2015
- Nebivolol to attenuate the effects of hyper-homocysteinaemia in rats. Akgullu C.et al,Atherosclerosis.,2015
- Nebivolol to attenuate the effects of hyper-homocysteinaemia in rats Cagdas Akgullu et al,Atherosclerosis,2015
- Metformin Eased Cognitive Impairment Induced by Chronic L-methionine Administration: Potential Role of Oxidative Stress H. Alzoubi et al,Current Neuropharmacology,,2014
- Proteomic analysis of one-carbon metabolism-related marker in liver of rat offspring You YA. et al,Mol Cell Proteomics,2015
- Characteristics of bone turnover, bone mass and bone strength in Spontaneously Diabetic Torii-Lepr fa rats /,Journal of Bone and Mineral Metabolism,2012
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