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中文名稱：人氧化低密度脂蛋白(OxLDL)酶聯免疫試劑盒
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貨號：CSB-E07931h
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規格：96T/48T
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價格：￥3600/￥2500
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其他：
產品詳情
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產品描述：人氧化低密度脂蛋白(OxLDL)酶聯免疫試劑盒（CSB-E07931h）為競爭法ELISA試劑盒，定量檢測血清、血漿、尿液、唾液、組織勻漿、細胞裂解物樣本中的OxLDL含量。OxLDL即氧化型低密度脂蛋白，是一種被氧化修飾的脂蛋白。它與動脈粥樣硬化等疾病密切相關。其研究機制主要聚焦在它可被巨噬細胞攝取形成泡沫細胞，還能引發炎癥反應，損傷血管內皮細胞，促進動脈粥樣硬化斑塊形成。試劑盒檢測范圍為1.56 mU/mL-100 mU/mL，本試劑盒可應用于心血管疾病基礎研究、氧化應激相關代謝機制探索、藥物或天然產物抗氧化效價評估等科研領域，為體外實驗提供高靈敏度的檢測方案，但不適用于臨床診斷。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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縮寫：OxLDL
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma, urine, saliva, tissue homogenates, cell lysates
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檢測范圍：1.56 mU/mL-100 mU/mL
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靈敏度：0.78 mU/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Others
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human OxLDL in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:100 Average % 99 Range % 93-105 1:200 Average % 94 Range % 91-98 1:400 Average % 103 Range % 99-107 1:800 Average % 86 Range % 80-92 -
回收率：
The recovery of human OxLDL spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 98 94-104 EDTA plasma (n=4) 94 88-97 -
標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
mU/ml OD1 OD2 Average 100 0.130 0.129 0.130 50 0.306 0.301 0.304 25 0.549 0.557 0.553 12.5 0.941 0.956 0.949 6.25 1.401 1.418 1.410 3.12 1.953 1.967 1.960 1.56 2.186 2.087 2.137 0 2.758 2.656 2.707 -
數據處理：
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貨期：3-5 working days
引用文獻
- Combined Citrulline and Glutathione Supplementation Improves Endothelial Function and Blood Pressure Reactivity in Postmenopausal Women C Citrulline, A Figueroa, A Maharaj, Y Kang, KN Dillon,Nutrients,2023
- ASOCIACIóN ENTRE LA COMPOSICIóN DE LA MICROBIOTA INTESTINAL Y LOS METABOLITOS INTESTINALES CON CITOCINAS PROINFLAMATORIAS Y MARCADORES DE ACTIVACIóN VASCULAR EN PACIENTES CON VIH Y ENFERMEDAD POR HíGADO GRASO NO ALCOHóLICO TEH AGUIRRE, ENCKS REYES, ENCMá ZAVALA,UNIVERSIDAD DE GUADALAJARA,/
- Activation of the inflammasome and pyroptosis cascade in podocytes of patients with minimal change disease Y Kajio,Clinical Kidney Journal,2024
- The Interplay between Atherosclerosis and Cancer: Breast Cancer Cells Increase the Expression of Endothelial Cell Adhesion Markers A Scalia,Biology,2023
- Oral Supplementation with Hydroxytyrosol Synthesized Using Genetically Modified Escherichia coli Strains and Essential Oils Mixture: A Pilot Study on the Safety and Biological Activity YV Simos,Microorganisms,2023
- Nontargeted Metabolomic Profiling of Huo-Tan-Chu-Shi Decoction in the Treatment of Coronary Heart Disease with Phlegm-damp Syndrome Z Liang,Cardiology research and practice,2022
- Caracterización y efectos de las LDL y HDL de mujeres con hipercolesterolemia durante el embarazo sobre la función vascular materna y de células endoteliales CA Cantín González,/,2022
- TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies A Akhmedov,Cardiovascular Research,2022
- Evaluation of the relationship between cardiac autonomic function and glucose variability and HOMA-IR in prediabetes R Dimova,Diabetes and Vascular Disease Research,2020
- The relationship between glucose variability and insulin sensitivity and oxidative stress in subjects with prediabetes Dimova R, et al,Diabetes Research and Clinical Practice,2019
- Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque Carnevale R.et al,Sci Rep,2018
- Curcumin pretreatment protects against PM2.5 Shi J.et al,Mol Med Rep,2017
- Homoarginine supplementation improves blood glucose in diet-induced obese mice Stockebrand M. et al,Amino Acids. ,2015
- Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo Akhmedov A et al,Eur Heart J,2014
- Association between Serum Ferritin and Circulating Oxidized Low-density Lipoprotein Levels in Patients with Coronary Artery Disease Ikeda Y et al,Endocr J,2012
- Green tea epigallocatechin-3-gallate attenuates Porphyromonas gingivalis-induced atherosclerosis Cai Y et al,Pathog Dis,2012
- Levels of oxidized LDL, estrogens and progesterone in placenta tissues and serum paraoxonase activity in preeclampsia Açikgöz S et al,Mediators Inflamm,2013
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