ZBP1
ZBP1，即Z-DNA結(jié)合蛋白1，別名DAI、DLM-1、ZBP。它是一種由ZBP1基因編碼的蛋白質(zhì)，在免疫細(xì)胞特別是自然殺傷（NK）細(xì)胞中表達(dá)。ZBP1的作用機(jī)制涉及識別并結(jié)合Z-DNA結(jié)構(gòu)，激活下游信號通路，如NF-κB，從而調(diào)控炎癥反應(yīng)和細(xì)胞死亡。ZBP1參與了細(xì)胞對病原體的免疫應(yīng)答，特別是通過促進(jìn)NK細(xì)胞的活化和細(xì)胞因子的產(chǎn)生來限制病原體的擴(kuò)散。此外，ZBP1還與細(xì)胞凋亡和壞死等程序性細(xì)胞死亡過程有關(guān)，影響細(xì)胞的生存和死亡。ZBP1的功能異常與某些疾病有關(guān)，包括自身免疫性疾病和某些類型的癌癥，是免疫學(xué)和細(xì)胞生物學(xué)研究中的一個(gè)重要分子靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Z-DNA-binding protein 1 (ZBP1) (CSB-EP861990HUb1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ZBP1 Antibodies
ZBP1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA026311GA01HU | ZBP1 Antibody | Human | ELISA,WB,IHC |
ZBP1 Proteins
ZBP1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP837712RA CSB-EP837712RA CSB-BP837712RA CSB-MP837712RA CSB-EP837712RA-B |
Recombinant Rat Z-DNA-binding protein 1 (Zbp1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ZBP1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP861990HU CSB-BP861990HU CSB-MP861990HU |
Recombinant Human Z-DNA-binding protein 1 (ZBP1) | Yeast Baculovirus Mammalian cell |
| CSB-EP861990HUb1 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HU | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HUb0 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HUf0 | Recombinant Human Z-DNA-binding protein 1 (ZBP1) | E.coli |
| CSB-EP861990HU-B | Recombinant Human Z-DNA-binding protein 1 (ZBP1), Biotinylated | E.coli |
ZBP1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP865587MO CSB-EP865587MO CSB-BP865587MO CSB-EP865587MO-B |
Recombinant Mouse Z-DNA-binding protein 1 (Zbp1) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
