YTHDF2
YTHDF2，別名DF2、CAHL、HGRG8、NY-REN-2。YTHDF2屬于YTH結(jié)構(gòu)域超家族成員，含有YTH結(jié)構(gòu)域，該結(jié)構(gòu)域通常位于蛋白質(zhì)序列的中間，與RNA結(jié)合。YTHDF2通過識別并結(jié)合N6-甲基腺苷（m6A）修飾的mRNA，調(diào)節(jié)這些mRNA的穩(wěn)定性和翻譯效率。YTHDF2在調(diào)控基因表達、mRNA代謝和細胞信號傳導中起重要作用。YTHDF2的功能異常與多種疾病相關(guān)，包括急性髓性白血病、視網(wǎng)膜色素變性、Wilms瘤等。
熱銷產(chǎn)品
Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial (CSB-EP896902HU2)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
YTHDF2 Antibody (CSB-PA896902LA01HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate
All lanes: YTHDF2 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 63, 57 kDa
Observed band size: 63, 50 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA896902LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA896902LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA896902LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
YTHDF2 Antibodies
YTHDF2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA896902LA01HU | YTHDF2 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA896902LB01HU | YTHDF2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA896902LC01HU | YTHDF2 Antibody, FITC conjugated | Human | |
| CSB-PA896902LD01HU | YTHDF2 Antibody, Biotin conjugated | Human | ELISA |
YTHDF2 Proteins
YTHDF2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP896902HU CSB-BP896902HU CSB-MP896902HU CSB-EP896902HU-B |
Recombinant Human YTH domain family protein 2 (YTHDF2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP896902HU | Recombinant Human YTH domain-containing family protein 2 (YTHDF2) | E.coli |
| CSB-EP896902HU2 | Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial | E.coli |
| CSB-EP896902HUc7 | Recombinant Human YTH domain-containing family protein 2 (YTHDF2) | E.coli |
| CSB-EP896902HU1 | Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial | E.coli |
