WIPI1
WD repeat domain phosphoinositide-interacting protein 1 is a protein in humans that is encoded by WIPI1 gene. Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.
WIPI1 Antibodies
WIPI1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA705810ESR2HU | WIPI1 Antibody | Human, Mouse | ELISA, WB, IHC |
WIPI1 Proteins
WIPI1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP705810HU CSB-EP705810HU CSB-BP705810HU CSB-MP705810HU CSB-EP705810HU-B |
Recombinant Human WD repeat domain phosphoinositide-interacting protein 1 (WIPI1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WIPI1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP718719XBE CSB-EP718719XBE CSB-BP718719XBE CSB-MP718719XBE CSB-EP718719XBE-B |
Recombinant Xenopus laevis WD repeat domain phosphoinositide-interacting protein 1 (wipi1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
WIPI1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP851264MO CSB-EP851264MO CSB-BP851264MO CSB-MP851264MO CSB-EP851264MO-B |
Recombinant Mouse WD repeat domain phosphoinositide-interacting protein 1 (Wipi1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
