USP8
Ubiquitin carboxyl-terminal hydrolase 8 is a protein in humans that is encoded by USP8 gene. Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability.
USP8 Antibodies
USP8 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025752ESR2HU | USP8 Antibody | Human | ELISA, WB, IHC |
USP8 Proteins
USP8 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025752HU CSB-EP025752HU CSB-BP025752HU CSB-MP025752HU CSB-EP025752HU-B |
Recombinant Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP8 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP768878MO CSB-EP768878MO CSB-BP768878MO CSB-MP768878MO CSB-EP768878MO-B |
Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase 8 (Usp8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
