TNC
TNC，即神經(jīng)膠質(zhì)素C，別名Tenascin-C、TN，是一種廣泛分布于細(xì)胞外基質(zhì)中的大型糖蛋白，主要由成纖維細(xì)胞、內(nèi)皮細(xì)胞和平滑肌細(xì)胞等分泌。TNC具有獨(dú)特的多域結(jié)構(gòu)，能夠與多種細(xì)胞表面受體（如整合素、Notch受體）及其它細(xì)胞外基質(zhì)成分相互作用，通過調(diào)節(jié)細(xì)胞粘附、遷移、增殖和分化等過程，參與組織的發(fā)育、重塑及修復(fù)。在生理狀態(tài)下，TNC對(duì)于維持組織穩(wěn)態(tài)和促進(jìn)傷口愈合具有重要作用。然而，在病理?xiàng)l件下，如腫瘤發(fā)生發(fā)展過程中，TNC的異常高表達(dá)可促進(jìn)癌細(xì)胞的侵襲和轉(zhuǎn)移，參與構(gòu)建有利于腫瘤生長(zhǎng)的微環(huán)境，成為疾病進(jìn)展的關(guān)鍵因素之一。此外，TNC還與慢性炎癥、纖維化等疾病相關(guān)，顯示出其在多種生物學(xué)過程中的復(fù)雜角色。
熱銷產(chǎn)品
TNC Antibody (CSB-PA11509A0Rb)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA11509A0Rb at dilution of 1:50
TNC Antibodies
TNC for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA11504D0Rb | TNC Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA11509C0Rb | TNC Antibody, FITC conjugated | Human | |
| CSB-PA11509A0Rb | TNC Antibody | Human | ELISA, IHC |
| CSB-PA11504A0Rb | TNC Antibody | Human | ELISA, IHC |
| CSB-PA11509D0Rb | TNC Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA11509B0Rb | TNC Antibody, HRP conjugated | Human | ELISA |
| CSB-PA006110 | TNC Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA296975 | TNC Antibody | Human,Mouse | ELISA,IHC |
TNC Proteins
TNC Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023954CH CSB-EP023954CH CSB-BP023954CH CSB-MP023954CH CSB-EP023954CH-B |
Recombinant Chicken Tenascin (TNC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNC Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023954HU CSB-EP023954HU CSB-BP023954HU CSB-MP023954HU CSB-EP023954HU-B |
Recombinant Human Tenascin (TNC), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP023954HU1a0 | Recombinant Human Tenascin (TNC), partial | E.coli |
TNC Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-BP642747PI CSB-MP642747PI CSB-EP642747PI-B |
Recombinant Pig Tenascin (TNC), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TNC Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP768917MO | Recombinant Mouse Tenascin (Tnc), partial | Yeast |
| CSB-EP768917MO CSB-EP768917MO-B |
Recombinant Mouse Tenascin (Tnc), partial | E.coli In Vivo Biotinylation in E.coli |
| CSB-BP768917MO | Recombinant Mouse Tenascin (Tnc), partial | Baculovirus |
| CSB-MP768917MO | Recombinant Mouse Tenascin (Tnc), partial | Mammalian cell |
TNC ELISA Kit
TNC ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL023954MO | Mouse Tenascin(TNC) ELISA kit | serum, plasma, tissue homogenates | 2.34 pg/mL |
TNC ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13125h | Human Tenascin-c (TNC) ELISA Kit |
